Sensing of glucose in the gastrointestinal tract

Helen E Raybould

doi:10.1016/j.autneu.2007.01.006

Sensing of glucose in the gastrointestinal tract

Helen E Raybould

Anatomy, Physiology and Cell Biology

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

In general, nutrient sensing mechanisms in the intestine are not well understood. Potential sensors include the terminals of extrinsic afferent nerves, enteric nerves, endocrine cells and other epithelial cells including enterocytes and immune cells. This short review will concentrate on the neural pathways that are activated by the presence of glucose in the intestinal lumen and the role of a specialized endocrine cell, the enterochromaffin cell in glucose-sensing and the subsequent activation of extrinsic neural pathways.

Original language	English (US)
Pages (from-to)	86-90
Number of pages	5
Journal	Autonomic Neuroscience: Basic and Clinical
Volume	133
Issue number	1
DOIs	https://doi.org/10.1016/j.autneu.2007.01.006
State	Published - Apr 30 2007

Keywords

5-hydroxytryptamine
Glucose
SGLT
Vagal afferent

ASJC Scopus subject areas

Clinical Neurology
Cellular and Molecular Neuroscience
Endocrine and Autonomic Systems

Access to Document

10.1016/j.autneu.2007.01.006

Cite this

@article{506aa3a14ac64d3e96a0acd11ff54e30,

title = "Sensing of glucose in the gastrointestinal tract",

abstract = "In general, nutrient sensing mechanisms in the intestine are not well understood. Potential sensors include the terminals of extrinsic afferent nerves, enteric nerves, endocrine cells and other epithelial cells including enterocytes and immune cells. This short review will concentrate on the neural pathways that are activated by the presence of glucose in the intestinal lumen and the role of a specialized endocrine cell, the enterochromaffin cell in glucose-sensing and the subsequent activation of extrinsic neural pathways.",

keywords = "5-hydroxytryptamine, Glucose, SGLT, Vagal afferent",

author = "Raybould, {Helen E}",

year = "2007",

month = apr,

day = "30",

doi = "10.1016/j.autneu.2007.01.006",

language = "English (US)",

volume = "133",

pages = "86--90",

journal = "Journal of the Autonomic Nervous System",

issn = "1566-0702",

publisher = "Elsevier",

number = "1",

}

TY - JOUR

T1 - Sensing of glucose in the gastrointestinal tract

AU - Raybould, Helen E

PY - 2007/4/30

Y1 - 2007/4/30

N2 - In general, nutrient sensing mechanisms in the intestine are not well understood. Potential sensors include the terminals of extrinsic afferent nerves, enteric nerves, endocrine cells and other epithelial cells including enterocytes and immune cells. This short review will concentrate on the neural pathways that are activated by the presence of glucose in the intestinal lumen and the role of a specialized endocrine cell, the enterochromaffin cell in glucose-sensing and the subsequent activation of extrinsic neural pathways.

AB - In general, nutrient sensing mechanisms in the intestine are not well understood. Potential sensors include the terminals of extrinsic afferent nerves, enteric nerves, endocrine cells and other epithelial cells including enterocytes and immune cells. This short review will concentrate on the neural pathways that are activated by the presence of glucose in the intestinal lumen and the role of a specialized endocrine cell, the enterochromaffin cell in glucose-sensing and the subsequent activation of extrinsic neural pathways.

KW - 5-hydroxytryptamine

KW - Glucose

KW - SGLT

KW - Vagal afferent

UR - http://www.scopus.com/inward/record.url?scp=33947573919&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33947573919&partnerID=8YFLogxK

U2 - 10.1016/j.autneu.2007.01.006

DO - 10.1016/j.autneu.2007.01.006

M3 - Article

C2 - 17324638

AN - SCOPUS:33947573919

VL - 133

SP - 86

EP - 90

JO - Journal of the Autonomic Nervous System

JF - Journal of the Autonomic Nervous System

SN - 1566-0702

IS - 1

ER -

Sensing of glucose in the gastrointestinal tract

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this