Sensing of glucose in the gastrointestinal tract

Helen E Raybould

doi:10.1016/j.autneu.2007.01.006

Sensing of glucose in the gastrointestinal tract

Helen E Raybould

Anatomy, Physiology and Cell Biology

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

In general, nutrient sensing mechanisms in the intestine are not well understood. Potential sensors include the terminals of extrinsic afferent nerves, enteric nerves, endocrine cells and other epithelial cells including enterocytes and immune cells. This short review will concentrate on the neural pathways that are activated by the presence of glucose in the intestinal lumen and the role of a specialized endocrine cell, the enterochromaffin cell in glucose-sensing and the subsequent activation of extrinsic neural pathways.

Original language	English (US)
Pages (from-to)	86-90
Number of pages	5
Journal	Autonomic Neuroscience: Basic and Clinical
Volume	133
Issue number	1
DOIs	https://doi.org/10.1016/j.autneu.2007.01.006
State	Published - Apr 30 2007

Keywords

5-hydroxytryptamine
Glucose
SGLT
Vagal afferent

ASJC Scopus subject areas

Clinical Neurology
Cellular and Molecular Neuroscience
Endocrine and Autonomic Systems

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