Sensing of glucose in the gastrointestinal tract

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

In general, nutrient sensing mechanisms in the intestine are not well understood. Potential sensors include the terminals of extrinsic afferent nerves, enteric nerves, endocrine cells and other epithelial cells including enterocytes and immune cells. This short review will concentrate on the neural pathways that are activated by the presence of glucose in the intestinal lumen and the role of a specialized endocrine cell, the enterochromaffin cell in glucose-sensing and the subsequent activation of extrinsic neural pathways.

Original languageEnglish (US)
Pages (from-to)86-90
Number of pages5
JournalAutonomic Neuroscience: Basic and Clinical
Volume133
Issue number1
DOIs
StatePublished - Apr 30 2007

Keywords

  • 5-hydroxytryptamine
  • Glucose
  • SGLT
  • Vagal afferent

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Endocrine and Autonomic Systems

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