Abstract
In general, nutrient sensing mechanisms in the intestine are not well understood. Potential sensors include the terminals of extrinsic afferent nerves, enteric nerves, endocrine cells and other epithelial cells including enterocytes and immune cells. This short review will concentrate on the neural pathways that are activated by the presence of glucose in the intestinal lumen and the role of a specialized endocrine cell, the enterochromaffin cell in glucose-sensing and the subsequent activation of extrinsic neural pathways.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 86-90 |
| Number of pages | 5 |
| Journal | Autonomic Neuroscience: Basic and Clinical |
| Volume | 133 |
| Issue number | 1 |
| DOIs | |
| State | Published - Apr 30 2007 |
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Keywords
- 5-hydroxytryptamine
- Glucose
- SGLT
- Vagal afferent
ASJC Scopus subject areas
- Clinical Neurology
- Cellular and Molecular Neuroscience
- Endocrine and Autonomic Systems
Cite this
Sensing of glucose in the gastrointestinal tract. / Raybould, Helen E.
In: Autonomic Neuroscience: Basic and Clinical, Vol. 133, No. 1, 30.04.2007, p. 86-90.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Sensing of glucose in the gastrointestinal tract
AU - Raybould, Helen E
PY - 2007/4/30
Y1 - 2007/4/30
N2 - In general, nutrient sensing mechanisms in the intestine are not well understood. Potential sensors include the terminals of extrinsic afferent nerves, enteric nerves, endocrine cells and other epithelial cells including enterocytes and immune cells. This short review will concentrate on the neural pathways that are activated by the presence of glucose in the intestinal lumen and the role of a specialized endocrine cell, the enterochromaffin cell in glucose-sensing and the subsequent activation of extrinsic neural pathways.
AB - In general, nutrient sensing mechanisms in the intestine are not well understood. Potential sensors include the terminals of extrinsic afferent nerves, enteric nerves, endocrine cells and other epithelial cells including enterocytes and immune cells. This short review will concentrate on the neural pathways that are activated by the presence of glucose in the intestinal lumen and the role of a specialized endocrine cell, the enterochromaffin cell in glucose-sensing and the subsequent activation of extrinsic neural pathways.
KW - 5-hydroxytryptamine
KW - Glucose
KW - SGLT
KW - Vagal afferent
UR - http://www.scopus.com/inward/record.url?scp=33947573919&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33947573919&partnerID=8YFLogxK
U2 - 10.1016/j.autneu.2007.01.006
DO - 10.1016/j.autneu.2007.01.006
M3 - Article
C2 - 17324638
AN - SCOPUS:33947573919
VL - 133
SP - 86
EP - 90
JO - Autonomic Neuroscience: Basic and Clinical
JF - Autonomic Neuroscience: Basic and Clinical
SN - 1566-0702
IS - 1
ER -