Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood

Dong Sik Shin; Zimple Matharu; Jungmok You; Christian Siltanen; Tam Vu; Vijay Krishna Raghunathan; Gulnaz Stybayeva; Ashley E Hill; Alexander Revzin

doi:10.1002/adhm.201500571

Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood

Dong Sik Shin, Zimple Matharu, Jungmok You, Christian Siltanen, Tam Vu, Vijay Krishna Raghunathan, Gulnaz Stybayeva, Ashley E Hill, Alexander Revzin

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Conducting polymer hydrogel is fabricated atop gold or ITO electrodes and is functionalized with monoclonal antibodies. Binding of interferon-γ molecules causes redox properties of conductive hydrogel to change in a concentration-dependent fashion without the need for washing or sample handling steps. This conductive hydrogel remains functional in a fouling media such as whole blood.

Original language	English (US)
Pages (from-to)	659-664
Number of pages	6
Journal	Advanced healthcare materials
Volume	5
Issue number	6
DOIs	https://doi.org/10.1002/adhm.201500571
State	Published - Mar 23 2016

Keywords

Biosensors
Conducting polymer hydrogels
Cytokine detection
Electrochemical detection
Immunoassays

ASJC Scopus subject areas

Biomedical Engineering
Biomaterials
Pharmaceutical Science

Access to Document

10.1002/adhm.201500571

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Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood. / Shin, Dong Sik; Matharu, Zimple; You, Jungmok; Siltanen, Christian; Vu, Tam; Raghunathan, Vijay Krishna; Stybayeva, Gulnaz; Hill, Ashley E; Revzin, Alexander.

In: Advanced healthcare materials, Vol. 5, No. 6, 23.03.2016, p. 659-664.

Research output: Contribution to journal › Article › peer-review

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