Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood

Dong Sik Shin; Zimple Matharu; Jungmok You; Christian Siltanen; Tam Vu; Vijay Krishna Raghunathan; Gulnaz Stybayeva; Ashley E Hill; Alexander Revzin

doi:10.1002/adhm.201500571

Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood

Dong Sik Shin, Zimple Matharu, Jungmok You, Christian Siltanen, Tam Vu, Vijay Krishna Raghunathan, Gulnaz Stybayeva, Ashley E Hill, Alexander Revzin

Research output: Contribution to journal › Article

9 Scopus citations

Abstract

Conducting polymer hydrogel is fabricated atop gold or ITO electrodes and is functionalized with monoclonal antibodies. Binding of interferon-γ molecules causes redox properties of conductive hydrogel to change in a concentration-dependent fashion without the need for washing or sample handling steps. This conductive hydrogel remains functional in a fouling media such as whole blood.

Original language	English (US)
Pages (from-to)	659-664
Number of pages	6
Journal	Advanced healthcare materials
Volume	5
Issue number	6
DOIs	https://doi.org/10.1002/adhm.201500571
State	Published - Mar 23 2016

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Keywords

Biosensors
Conducting polymer hydrogels
Cytokine detection
Electrochemical detection
Immunoassays

ASJC Scopus subject areas

Biomedical Engineering
Biomaterials
Pharmaceutical Science

Cite this

Shin, D. S., Matharu, Z., You, J., Siltanen, C., Vu, T., Raghunathan, V. K., Stybayeva, G., Hill, A. E., & Revzin, A. (2016). Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood. Advanced healthcare materials, 5(6), 659-664. https://doi.org/10.1002/adhm.201500571

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Access to Document

10.1002/adhm.201500571