Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood

Dong Sik Shin, Zimple Matharu, Jungmok You, Christian Siltanen, Tam Vu, Vijay Krishna Raghunathan, Gulnaz Stybayeva, Ashley E Hill, Alexander Revzin

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Conducting polymer hydrogel is fabricated atop gold or ITO electrodes and is functionalized with monoclonal antibodies. Binding of interferon-γ molecules causes redox properties of conductive hydrogel to change in a concentration-dependent fashion without the need for washing or sample handling steps. This conductive hydrogel remains functional in a fouling media such as whole blood.

Original languageEnglish (US)
Pages (from-to)659-664
Number of pages6
JournalAdvanced healthcare materials
Volume5
Issue number6
DOIs
StatePublished - Mar 23 2016

Fingerprint

Hydrogels
Hydrogel
Blood
Cytokines
Interferons
Monoclonal antibodies
Conducting polymers
Fouling
Washing
Gold
Oxidation-Reduction
Polymers
Electrodes
Monoclonal Antibodies
Molecules

Keywords

  • Biosensors
  • Conducting polymer hydrogels
  • Cytokine detection
  • Electrochemical detection
  • Immunoassays

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Pharmaceutical Science

Cite this

Shin, D. S., Matharu, Z., You, J., Siltanen, C., Vu, T., Raghunathan, V. K., ... Revzin, A. (2016). Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood. Advanced healthcare materials, 5(6), 659-664. https://doi.org/10.1002/adhm.201500571

Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood. / Shin, Dong Sik; Matharu, Zimple; You, Jungmok; Siltanen, Christian; Vu, Tam; Raghunathan, Vijay Krishna; Stybayeva, Gulnaz; Hill, Ashley E; Revzin, Alexander.

In: Advanced healthcare materials, Vol. 5, No. 6, 23.03.2016, p. 659-664.

Research output: Contribution to journalArticle

Shin, DS, Matharu, Z, You, J, Siltanen, C, Vu, T, Raghunathan, VK, Stybayeva, G, Hill, AE & Revzin, A 2016, 'Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood', Advanced healthcare materials, vol. 5, no. 6, pp. 659-664. https://doi.org/10.1002/adhm.201500571
Shin DS, Matharu Z, You J, Siltanen C, Vu T, Raghunathan VK et al. Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood. Advanced healthcare materials. 2016 Mar 23;5(6):659-664. https://doi.org/10.1002/adhm.201500571
Shin, Dong Sik ; Matharu, Zimple ; You, Jungmok ; Siltanen, Christian ; Vu, Tam ; Raghunathan, Vijay Krishna ; Stybayeva, Gulnaz ; Hill, Ashley E ; Revzin, Alexander. / Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood. In: Advanced healthcare materials. 2016 ; Vol. 5, No. 6. pp. 659-664.
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