Abstract
Conducting polymer hydrogel is fabricated atop gold or ITO electrodes and is functionalized with monoclonal antibodies. Binding of interferon-γ molecules causes redox properties of conductive hydrogel to change in a concentration-dependent fashion without the need for washing or sample handling steps. This conductive hydrogel remains functional in a fouling media such as whole blood.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 659-664 |
| Number of pages | 6 |
| Journal | Advanced healthcare materials |
| Volume | 5 |
| Issue number | 6 |
| DOIs | |
| State | Published - Mar 23 2016 |
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Keywords
- Biosensors
- Conducting polymer hydrogels
- Cytokine detection
- Electrochemical detection
- Immunoassays
ASJC Scopus subject areas
- Biomedical Engineering
- Biomaterials
- Pharmaceutical Science
Cite this
Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood. / Shin, Dong Sik; Matharu, Zimple; You, Jungmok; Siltanen, Christian; Vu, Tam; Raghunathan, Vijay Krishna; Stybayeva, Gulnaz; Hill, Ashley E; Revzin, Alexander.
In: Advanced healthcare materials, Vol. 5, No. 6, 23.03.2016, p. 659-664.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood
AU - Shin, Dong Sik
AU - Matharu, Zimple
AU - You, Jungmok
AU - Siltanen, Christian
AU - Vu, Tam
AU - Raghunathan, Vijay Krishna
AU - Stybayeva, Gulnaz
AU - Hill, Ashley E
AU - Revzin, Alexander
PY - 2016/3/23
Y1 - 2016/3/23
N2 - Conducting polymer hydrogel is fabricated atop gold or ITO electrodes and is functionalized with monoclonal antibodies. Binding of interferon-γ molecules causes redox properties of conductive hydrogel to change in a concentration-dependent fashion without the need for washing or sample handling steps. This conductive hydrogel remains functional in a fouling media such as whole blood.
AB - Conducting polymer hydrogel is fabricated atop gold or ITO electrodes and is functionalized with monoclonal antibodies. Binding of interferon-γ molecules causes redox properties of conductive hydrogel to change in a concentration-dependent fashion without the need for washing or sample handling steps. This conductive hydrogel remains functional in a fouling media such as whole blood.
KW - Biosensors
KW - Conducting polymer hydrogels
KW - Cytokine detection
KW - Electrochemical detection
KW - Immunoassays
UR - http://www.scopus.com/inward/record.url?scp=84955612681&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84955612681&partnerID=8YFLogxK
U2 - 10.1002/adhm.201500571
DO - 10.1002/adhm.201500571
M3 - Article
C2 - 26799538
AN - SCOPUS:84955612681
VL - 5
SP - 659
EP - 664
JO - Advanced healthcare materials
JF - Advanced healthcare materials
SN - 2192-2640
IS - 6
ER -