Semiautomated renal region-of-interest selection method: validation in a dog model

W. J. Hornof, Larry D Cowgill, G. R. Conrad, P. Fisher

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


A successful method of automated region-of-interest (ROI) selection by polar edge search for use in technetium-99m-diethylenetriaminepentacetate (99mTc-DTPA) renography is presented in a dog model. The accuracy of the resultant ROI was tested by comparing renal uptake within the ROI to simultaneously monitored arterial 99mTc-DTPA concentration. The automatically selected ROI resulted in renal uptake curves that better matched arterial clearance than either systematically larger and smaller ROIs or a manually chosen ROI.

Original languageEnglish (US)
Pages (from-to)133-138
Number of pages6
JournalAmerican Journal of Physiologic Imaging
Issue number3
StatePublished - 1988

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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