Self-selection and the obese Zucker rat: The effect of dietary fat dilution

Thomas W. Castonguay, Sheri L. Burdick, Maria A. Guzman, George H. Collier, Judith S. Stern

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Adult female lean and obese Zucker rats were allowed to compose their own diets by giving them access to three macronutrient sources. After a baseline period, the fat source was serially diluted. In all, eight concentrations of fat were used. Dilution of the fat source promoted significant increases in the intake of fat by both lean and obese rats. The increased intake of fat was not simply compensatory in nature, but rather represented significant increases in fat consumption. These results suggest that the reported increased appetite for fat of the obese rat is not a unique trait of that genotype. Further, results from this experiment demonstrate that caloric and protein regulation mechanisms may not be controlling the intake of obese and lean rats as precisely as once believed.

Original languageEnglish (US)
Pages (from-to)119-126
Number of pages8
JournalPhysiology and Behavior
Volume33
Issue number1
DOIs
StatePublished - 1984

Keywords

  • Caloric regulation
  • Diet selection
  • Dilution
  • Motivation

ASJC Scopus subject areas

  • Physiology (medical)
  • Behavioral Neuroscience

Fingerprint Dive into the research topics of 'Self-selection and the obese Zucker rat: The effect of dietary fat dilution'. Together they form a unique fingerprint.

  • Cite this

    Castonguay, T. W., Burdick, S. L., Guzman, M. A., Collier, G. H., & Stern, J. S. (1984). Self-selection and the obese Zucker rat: The effect of dietary fat dilution. Physiology and Behavior, 33(1), 119-126. https://doi.org/10.1016/0031-9384(84)90022-2