Self-normalization of emission data in 3D PET

Ramsey D Badawi, P. K. Marsden

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

We demonstrate that dead-time mismatch between the normalization and emission acquisitions in three-dimensional positron emission tomography (3D PET) can introduce highfrequency circular image artifacts. We describe a simple correction scheme for this problem where appropriate correction factors are calculated from the emission data itself, thus avoiding the necessity of acquiring normalization data at a range of different count-rates. In this scheme "pseudo detector efficiencies" are calculated from the emission data by application of a conventional normalization algorithm. The mean systematic variation in these pseudo-efficiencies with position within the block-detector is then calculated, and appropriate correction factors applied to the original emission data. We show that this "self-normalization" scheme can remove normalization artifacts in both uniform and nonuniform phantom studies, and that it is also effective in vivo.

Original languageEnglish (US)
Pages (from-to)709-712
Number of pages4
JournalIEEE Transactions on Nuclear Science
Volume46
Issue number3 PART 2
DOIs
StatePublished - 1999
Externally publishedYes

Fingerprint

Detectors
Positron emission tomography
artifacts
detectors
positrons
acquisition
tomography

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Nuclear Energy and Engineering

Cite this

Self-normalization of emission data in 3D PET. / Badawi, Ramsey D; Marsden, P. K.

In: IEEE Transactions on Nuclear Science, Vol. 46, No. 3 PART 2, 1999, p. 709-712.

Research output: Contribution to journalArticle

Badawi, Ramsey D ; Marsden, P. K. / Self-normalization of emission data in 3D PET. In: IEEE Transactions on Nuclear Science. 1999 ; Vol. 46, No. 3 PART 2. pp. 709-712.
@article{e7525928bcef413a81e87c8f7112250e,
title = "Self-normalization of emission data in 3D PET",
abstract = "We demonstrate that dead-time mismatch between the normalization and emission acquisitions in three-dimensional positron emission tomography (3D PET) can introduce highfrequency circular image artifacts. We describe a simple correction scheme for this problem where appropriate correction factors are calculated from the emission data itself, thus avoiding the necessity of acquiring normalization data at a range of different count-rates. In this scheme {"}pseudo detector efficiencies{"} are calculated from the emission data by application of a conventional normalization algorithm. The mean systematic variation in these pseudo-efficiencies with position within the block-detector is then calculated, and appropriate correction factors applied to the original emission data. We show that this {"}self-normalization{"} scheme can remove normalization artifacts in both uniform and nonuniform phantom studies, and that it is also effective in vivo.",
author = "Badawi, {Ramsey D} and Marsden, {P. K.}",
year = "1999",
doi = "10.1109/23.775603",
language = "English (US)",
volume = "46",
pages = "709--712",
journal = "IEEE Transactions on Nuclear Science",
issn = "0018-9499",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
number = "3 PART 2",

}

TY - JOUR

T1 - Self-normalization of emission data in 3D PET

AU - Badawi, Ramsey D

AU - Marsden, P. K.

PY - 1999

Y1 - 1999

N2 - We demonstrate that dead-time mismatch between the normalization and emission acquisitions in three-dimensional positron emission tomography (3D PET) can introduce highfrequency circular image artifacts. We describe a simple correction scheme for this problem where appropriate correction factors are calculated from the emission data itself, thus avoiding the necessity of acquiring normalization data at a range of different count-rates. In this scheme "pseudo detector efficiencies" are calculated from the emission data by application of a conventional normalization algorithm. The mean systematic variation in these pseudo-efficiencies with position within the block-detector is then calculated, and appropriate correction factors applied to the original emission data. We show that this "self-normalization" scheme can remove normalization artifacts in both uniform and nonuniform phantom studies, and that it is also effective in vivo.

AB - We demonstrate that dead-time mismatch between the normalization and emission acquisitions in three-dimensional positron emission tomography (3D PET) can introduce highfrequency circular image artifacts. We describe a simple correction scheme for this problem where appropriate correction factors are calculated from the emission data itself, thus avoiding the necessity of acquiring normalization data at a range of different count-rates. In this scheme "pseudo detector efficiencies" are calculated from the emission data by application of a conventional normalization algorithm. The mean systematic variation in these pseudo-efficiencies with position within the block-detector is then calculated, and appropriate correction factors applied to the original emission data. We show that this "self-normalization" scheme can remove normalization artifacts in both uniform and nonuniform phantom studies, and that it is also effective in vivo.

UR - http://www.scopus.com/inward/record.url?scp=0033330464&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033330464&partnerID=8YFLogxK

U2 - 10.1109/23.775603

DO - 10.1109/23.775603

M3 - Article

VL - 46

SP - 709

EP - 712

JO - IEEE Transactions on Nuclear Science

JF - IEEE Transactions on Nuclear Science

SN - 0018-9499

IS - 3 PART 2

ER -