Self-assembled monolayers

A versatile tool for biofunctionalization of surfaces

Atul N. Parikh, David L. Allara

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Molecular-level control over surface chemistry and topology is critical for the design of biologically active synthetic surfaces. Such surfaces must present active biological ligands in defined conformations, orientations, concentrations, and spatial distributions so as to foster biospecific interactions and inhibit nonspecific ones. Self-assembled monolayers (SAMs)-spontaneously organized monomolecular assemblies at solid surfaces-provide an elegant and versatile means to endow synthetic surfaces with such exquisite level of control at the molecular level. This chapter reviews the essential physical-chemical foundation for the preparation, structure, and formation mechanisms of SAMs; presents their amenability for spatial control using tools of micro-and nanopatterning; and highlights their enabling capacity for a broad range of biomolecular functionalization.

Original languageEnglish (US)
Title of host publicationHandbook of Biofunctional Surfaces
PublisherPan Stanford Publishing Pte. Ltd.
Pages1-29
Number of pages29
ISBN (Print)9789814316637
DOIs
StatePublished - Apr 30 2013

Fingerprint

Self assembled monolayers
Ligands
Level control
Surface chemistry
Crystal orientation
Spatial distribution
Conformations
Topology

ASJC Scopus subject areas

  • Medicine(all)
  • Materials Science(all)

Cite this

Parikh, A. N., & Allara, D. L. (2013). Self-assembled monolayers: A versatile tool for biofunctionalization of surfaces. In Handbook of Biofunctional Surfaces (pp. 1-29). Pan Stanford Publishing Pte. Ltd.. https://doi.org/10.4032/9789814364188

Self-assembled monolayers : A versatile tool for biofunctionalization of surfaces. / Parikh, Atul N.; Allara, David L.

Handbook of Biofunctional Surfaces. Pan Stanford Publishing Pte. Ltd., 2013. p. 1-29.

Research output: Chapter in Book/Report/Conference proceedingChapter

Parikh, AN & Allara, DL 2013, Self-assembled monolayers: A versatile tool for biofunctionalization of surfaces. in Handbook of Biofunctional Surfaces. Pan Stanford Publishing Pte. Ltd., pp. 1-29. https://doi.org/10.4032/9789814364188
Parikh AN, Allara DL. Self-assembled monolayers: A versatile tool for biofunctionalization of surfaces. In Handbook of Biofunctional Surfaces. Pan Stanford Publishing Pte. Ltd. 2013. p. 1-29 https://doi.org/10.4032/9789814364188
Parikh, Atul N. ; Allara, David L. / Self-assembled monolayers : A versatile tool for biofunctionalization of surfaces. Handbook of Biofunctional Surfaces. Pan Stanford Publishing Pte. Ltd., 2013. pp. 1-29
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