TY - JOUR
T1 - Selective potentiation of retinal horizontal cell responses to l-glutamate by d-aspartate
AU - Ishida, Andrew
PY - 1982
Y1 - 1982
N2 - 1. l-Glutamate and l-aspartate depolarize type H1 horizontal cells in the isolated retina of goldfish, but only at millimolar concentrations. 2. When applied in the presence of d-aspartate, l-glutamate depolarizes H1 cells at concentrations nearly 15-fold lower than when it is applied alone. The effects of l-aspartate were not potentiated by either d-aspartate or d-glutamate. 3. Since d-aspartate seems also to enhance the effect of the transmitter released by cone photoreceptors, these results are consistent with the possibility that l-glutamate is a neurotransmitter of cones.
AB - 1. l-Glutamate and l-aspartate depolarize type H1 horizontal cells in the isolated retina of goldfish, but only at millimolar concentrations. 2. When applied in the presence of d-aspartate, l-glutamate depolarizes H1 cells at concentrations nearly 15-fold lower than when it is applied alone. The effects of l-aspartate were not potentiated by either d-aspartate or d-glutamate. 3. Since d-aspartate seems also to enhance the effect of the transmitter released by cone photoreceptors, these results are consistent with the possibility that l-glutamate is a neurotransmitter of cones.
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U2 - 10.1016/0306-4492(82)90090-9
DO - 10.1016/0306-4492(82)90090-9
M3 - Article
C2 - 6128145
AN - SCOPUS:0019946843
VL - 72
SP - 241
EP - 247
JO - Comparative biochemistry and physiology. C: Comparative pharmacology
JF - Comparative biochemistry and physiology. C: Comparative pharmacology
SN - 0742-8413
IS - 2
ER -