Selective potentiation of retinal horizontal cell responses to l-glutamate by d-aspartate

Andrew Ishida

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

1. l-Glutamate and l-aspartate depolarize type H1 horizontal cells in the isolated retina of goldfish, but only at millimolar concentrations. 2. When applied in the presence of d-aspartate, l-glutamate depolarizes H1 cells at concentrations nearly 15-fold lower than when it is applied alone. The effects of l-aspartate were not potentiated by either d-aspartate or d-glutamate. 3. Since d-aspartate seems also to enhance the effect of the transmitter released by cone photoreceptors, these results are consistent with the possibility that l-glutamate is a neurotransmitter of cones.

Original languageEnglish (US)
Pages (from-to)241-247
Number of pages7
JournalComparative Biochemistry and Physiology. Part C, Comparative
Volume72
Issue number2
DOIs
StatePublished - 1982
Externally publishedYes

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Retinal Horizontal Cells
Aspartic Acid
Glutamic Acid
Retinal Cone Photoreceptor Cells
Goldfish
Neurotransmitter Agents
Retina

ASJC Scopus subject areas

  • Immunology
  • Pharmacology

Cite this

Selective potentiation of retinal horizontal cell responses to l-glutamate by d-aspartate. / Ishida, Andrew.

In: Comparative Biochemistry and Physiology. Part C, Comparative, Vol. 72, No. 2, 1982, p. 241-247.

Research output: Contribution to journalArticle

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