Selection of silk-binding peptides by phage display

Yoko Nomura, Vandana Sharma, Asami Yamamura, Yohei Yokobayashi

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Peptides that bind to silkworm-derived silk fibroin fiber were selected from a phage-displayed random peptide library. The selected silk-binding peptides contained a consensus sequence QSWS which is important for silk-binding as confirmed by binding assays using phage and synthetic peptides. With further optimization, we anticipate that the silk-binding peptides will be useful for functionalization of silk for biomaterial applications.

Original languageEnglish (US)
Pages (from-to)1069-1073
Number of pages5
JournalBiotechnology Letters
Issue number5
StatePublished - May 2011


  • Fibroin fiber
  • Peptide
  • Phage display
  • Silk

ASJC Scopus subject areas

  • Biotechnology


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