Abstract
The random synthetic peptide library screening method based on the "one-bead one-peptide concept" (Selectide Process) can be used as a general method for the identification of peptide substrate motif for post-translational modifications. We applied this method to the cAMP-dependent protein kinase system and were able to rapidly identify a peptide motif (RRXS) that exactly matched that described for its natural substrates.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 401-403 |
| Number of pages | 3 |
| Journal | Methods |
| Volume | 6 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 1994 |
| Externally published | Yes |
ASJC Scopus subject areas
- Molecular Biology
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Cite this
Lam, K., & Wu, J. (1994). Selectide Technology: Substrate Motif Identification for Post-translational Modifications. Methods, 6(4), 401-403. https://doi.org/10.1006/meth.1994.1041