Secondary supratentorial primitive neuroectodermal tumor following irradiation in a patient with low-grade astrocytoma

Allan Y. Chen, Haidy Lee, Jonathan Hartman, Claudia Greco, Janice K. Ryu, Robert T O'Donnell, James E Boggan

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

We report a case of a supratentorial primitive neuroectodermal tumor (PNET) that occurred 12 years after cranial irradiation for a grade II astrocytoma. Neuroimaging was unable to distinguish between a recurrence of the original neoplasm and the development of a new, distinct entity. Pathologic review assisted by immunohistochemical staining, however, revealed a high-grade PNET. Although rare, PNET needs to be included in the differential diagnoses for previously irradiated patients, who develop recurrent brain tumors in the presence of uncharacteristic imaging features.

Original languageEnglish (US)
Pages (from-to)160-162
Number of pages3
JournalAmerican Journal of Neuroradiology
Volume26
Issue number1
StatePublished - 2005

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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