Screening mammography beginning at age 40 years: A reappraisal of cost- effectiveness

C. John Rosenquist, Karen K Lindfors

Research output: Contribution to journalArticlepeer-review

62 Scopus citations


BACKGROUND. Several recent studies have added significant information regarding the benefit of screening mammography, especially in the 40-49- years age group. This new information makes it important to reassess the cost-effectiveness of screening. METHODS. A Markov model was used to study the cost-effectiveness of 4 age-related screening strategies: 1) annually from ages 40-79 years; 2) annually from ages 40-64 years and biennially from ages 65-79 years; 3) annually from ages 40-49 years and biennially from ages 50-79 years; and 4) annually from ages 40-79 years in high risk women (10%) and biennially from ages 40-49 years followed by annually from ages 50-79 years in normal risk women (90%). An additional strategy simulating hormone status and estrogen exposure was evaluated. Cost-effectiveness was expressed as marginal cost per year-life saved (MCYLS). RESULTS. The MCYLS varied from $18,800 to $16,100. For all strategies this was within the range of other generally acceptable diagnostic and therapeutic medical procedures. There was a 14% decrease in MCYLS from the least cost-effective to the most cost- effective strategy. CONCLUSIONS. Cost-effectiveness of four age-related mammographic screening strategies was evaluated. The MCYLS for all strategies was within a generally accepted range. With increasing concerns regarding the cost of health care, this information may be useful in health policy decision-making.

Original languageEnglish (US)
Pages (from-to)2235-2240
Number of pages6
Issue number11
StatePublished - Jun 1 1998


  • Breast
  • Carcinoma
  • Cost-effectiveness
  • Mammography
  • Screening

ASJC Scopus subject areas

  • Cancer Research
  • Oncology


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