TY - JOUR
T1 - SCREENING FOR CHLAMYDIA TRACHOMATIS AND NEISSERIA GONORRHOEAE IN ADOLESCENT MALES
T2 - VALUE OF FIRST-CATCH URINE EXAMINATION
AU - Adger, Hoover
AU - Sweet, Richard L
AU - Shafer, Mary Ann
AU - Schachter, Julius
PY - 1984/10/27
Y1 - 1984/10/27
N2 - 50 adolescent males attending a general teen clinic (aged 13-21) were evaluated for urethritis. After examination of sediment from the initial 15-20 ml of voided urine, first-catch urine (FCU), specimen urethral swabs were taken for culture of Chlamydia trachomatis and Neisseria gonorrhoeae. 21 of 23 (91%) males with >10 leucocytes per high-power field of resuspended sediment (FCU-positive) had positive urethral cultures for C trachomatis or N gonorrhoeae compared with only 1 of 27 (4%) FCU-negative subjects (p<0·001) 12 of 22 culture-positive subjects had no genitourinary symptoms and 11 of the 12 had C trachomatis infections. The sensitivity of FCU examination in identifying culture-positive urethritis was 95%, the specificity 93%, and the predictive value of a positive FCU 91%. FCU examination is a useful, non-invasive screening test to detect urethritis associated with C trachomatis and N gonorrhoeae. The test may be especially helpful in identifying symptom-free males with chlamydia-associated urethritis.
AB - 50 adolescent males attending a general teen clinic (aged 13-21) were evaluated for urethritis. After examination of sediment from the initial 15-20 ml of voided urine, first-catch urine (FCU), specimen urethral swabs were taken for culture of Chlamydia trachomatis and Neisseria gonorrhoeae. 21 of 23 (91%) males with >10 leucocytes per high-power field of resuspended sediment (FCU-positive) had positive urethral cultures for C trachomatis or N gonorrhoeae compared with only 1 of 27 (4%) FCU-negative subjects (p<0·001) 12 of 22 culture-positive subjects had no genitourinary symptoms and 11 of the 12 had C trachomatis infections. The sensitivity of FCU examination in identifying culture-positive urethritis was 95%, the specificity 93%, and the predictive value of a positive FCU 91%. FCU examination is a useful, non-invasive screening test to detect urethritis associated with C trachomatis and N gonorrhoeae. The test may be especially helpful in identifying symptom-free males with chlamydia-associated urethritis.
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U2 - 10.1016/S0140-6736(84)91164-4
DO - 10.1016/S0140-6736(84)91164-4
M3 - Article
C2 - 6149341
AN - SCOPUS:0021690114
VL - 324
SP - 944
EP - 945
JO - The Lancet
JF - The Lancet
SN - 0140-6736
IS - 8409
ER -