Abstract
Sclerosing mesenteritis is an uncommon nonneoplastic inflammatory process in the mesentery that is seen as a pseudotumor, usually involving the small bowel mesentery, the mesenteric fat, and less commonly, the mesentery of the large bowel. We report two cases of sclerosing mesenteritis and review the literature on this rare disease. Both patients had pain, profound weight loss, and a mass on computed tomography (CT) scan of the abdomen. The provisional diagnosis was pancreatic neoplasm on the basis of clinical presentation and imaging studies. The diagnosis of sclerosing mesenteritis was established by histologic findings in biopsy material obtained at laparotomy in both cases. Interval histologic studies in one patient who had a high CA 19-9 level, progressive biliary ductal and partial duodenal compression, revealed a transitional histologic pattern from predominant inflammation and fat necrosis to predominant fibrosis. This may explain the varied descriptive terms used in the literature to describe this entity.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 316-321 |
| Number of pages | 6 |
| Journal | Pancreas |
| Volume | 18 |
| Issue number | 3 |
| State | Published - Apr 1999 |
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Keywords
- Pancreas
- Pseudotumor
- Sclerosing mesenteritis
ASJC Scopus subject areas
- Gastroenterology
- Endocrinology
Cite this
Sclerosing mesenteritis seen clinically as pancreatic pseudotumor : Two cases and a review. / Sheikh, Rafiq A.; Prindiville, Thomas P; Arenson, D.; Ruebner, B. H.
In: Pancreas, Vol. 18, No. 3, 04.1999, p. 316-321.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Sclerosing mesenteritis seen clinically as pancreatic pseudotumor
T2 - Two cases and a review
AU - Sheikh, Rafiq A.
AU - Prindiville, Thomas P
AU - Arenson, D.
AU - Ruebner, B. H.
PY - 1999/4
Y1 - 1999/4
N2 - Sclerosing mesenteritis is an uncommon nonneoplastic inflammatory process in the mesentery that is seen as a pseudotumor, usually involving the small bowel mesentery, the mesenteric fat, and less commonly, the mesentery of the large bowel. We report two cases of sclerosing mesenteritis and review the literature on this rare disease. Both patients had pain, profound weight loss, and a mass on computed tomography (CT) scan of the abdomen. The provisional diagnosis was pancreatic neoplasm on the basis of clinical presentation and imaging studies. The diagnosis of sclerosing mesenteritis was established by histologic findings in biopsy material obtained at laparotomy in both cases. Interval histologic studies in one patient who had a high CA 19-9 level, progressive biliary ductal and partial duodenal compression, revealed a transitional histologic pattern from predominant inflammation and fat necrosis to predominant fibrosis. This may explain the varied descriptive terms used in the literature to describe this entity.
AB - Sclerosing mesenteritis is an uncommon nonneoplastic inflammatory process in the mesentery that is seen as a pseudotumor, usually involving the small bowel mesentery, the mesenteric fat, and less commonly, the mesentery of the large bowel. We report two cases of sclerosing mesenteritis and review the literature on this rare disease. Both patients had pain, profound weight loss, and a mass on computed tomography (CT) scan of the abdomen. The provisional diagnosis was pancreatic neoplasm on the basis of clinical presentation and imaging studies. The diagnosis of sclerosing mesenteritis was established by histologic findings in biopsy material obtained at laparotomy in both cases. Interval histologic studies in one patient who had a high CA 19-9 level, progressive biliary ductal and partial duodenal compression, revealed a transitional histologic pattern from predominant inflammation and fat necrosis to predominant fibrosis. This may explain the varied descriptive terms used in the literature to describe this entity.
KW - Pancreas
KW - Pseudotumor
KW - Sclerosing mesenteritis
UR - http://www.scopus.com/inward/record.url?scp=0033022154&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033022154&partnerID=8YFLogxK
M3 - Article
VL - 18
SP - 316
EP - 321
JO - Pancreas
JF - Pancreas
SN - 0885-3177
IS - 3
ER -