Scintigraphic detection of equine orthopedic infection using Tc-HMPAO labeled leukocytes in 14 horses

Craig D. Long; Larry D Galuppo; Ned K. Waters; William J. Hornof

Scintigraphic detection of equine orthopedic infection using Tc-HMPAO labeled leukocytes in 14 horses

Craig D. Long, Larry D Galuppo, Ned K. Waters, William J. Hornof

Surgical and Radiological Sciences

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

The aim of this study was to evaluate the diagnostic value of ^99mTc-HMPAO leukocyte scintigraphy (LS) by means of a retrospective review of its use in 14 horses that were evaluated for orthopedic infection as a cause of lameness. A total of 17 LS exams were performed in 14 horses. LS studies were positive in 10 of 14 horses. A bacterial infection was confirmed with cytology or culture in 9 of 10 positive horses. Negative LS studies occurred in 4 of 14 horses. Necropsy confirmed the lack of infection in 2 of the 4 horses. Other clinical data and a favorable clinical outcome supported a negative study in the other 2 horses. No false negative or false positive studies were identified. It may be concluded that HMPAO-LS is an effective tool for the diagnosis of orthopedic infection in horses.

Original language	English (US)
Pages (from-to)	354-359
Number of pages	6
Journal	Veterinary Radiology and Ultrasound
Volume	41
Issue number	4
State	Published - Jul 2000

Keywords

Equine
Infection
Leukocyte
Scintigraphy
Tc-HMPAO
Technetium-99m

ASJC Scopus subject areas

veterinary(all)

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title = "Scintigraphic detection of equine orthopedic infection using Tc-HMPAO labeled leukocytes in 14 horses",

abstract = "The aim of this study was to evaluate the diagnostic value of 99mTc-HMPAO leukocyte scintigraphy (LS) by means of a retrospective review of its use in 14 horses that were evaluated for orthopedic infection as a cause of lameness. A total of 17 LS exams were performed in 14 horses. LS studies were positive in 10 of 14 horses. A bacterial infection was confirmed with cytology or culture in 9 of 10 positive horses. Negative LS studies occurred in 4 of 14 horses. Necropsy confirmed the lack of infection in 2 of the 4 horses. Other clinical data and a favorable clinical outcome supported a negative study in the other 2 horses. No false negative or false positive studies were identified. It may be concluded that HMPAO-LS is an effective tool for the diagnosis of orthopedic infection in horses.",

keywords = "Equine, Infection, Leukocyte, Scintigraphy, Tc-HMPAO, Technetium-99m",

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AU - Long, Craig D.

AU - Galuppo, Larry D

AU - Waters, Ned K.

AU - Hornof, William J.

PY - 2000/7

Y1 - 2000/7

N2 - The aim of this study was to evaluate the diagnostic value of 99mTc-HMPAO leukocyte scintigraphy (LS) by means of a retrospective review of its use in 14 horses that were evaluated for orthopedic infection as a cause of lameness. A total of 17 LS exams were performed in 14 horses. LS studies were positive in 10 of 14 horses. A bacterial infection was confirmed with cytology or culture in 9 of 10 positive horses. Negative LS studies occurred in 4 of 14 horses. Necropsy confirmed the lack of infection in 2 of the 4 horses. Other clinical data and a favorable clinical outcome supported a negative study in the other 2 horses. No false negative or false positive studies were identified. It may be concluded that HMPAO-LS is an effective tool for the diagnosis of orthopedic infection in horses.

AB - The aim of this study was to evaluate the diagnostic value of 99mTc-HMPAO leukocyte scintigraphy (LS) by means of a retrospective review of its use in 14 horses that were evaluated for orthopedic infection as a cause of lameness. A total of 17 LS exams were performed in 14 horses. LS studies were positive in 10 of 14 horses. A bacterial infection was confirmed with cytology or culture in 9 of 10 positive horses. Negative LS studies occurred in 4 of 14 horses. Necropsy confirmed the lack of infection in 2 of the 4 horses. Other clinical data and a favorable clinical outcome supported a negative study in the other 2 horses. No false negative or false positive studies were identified. It may be concluded that HMPAO-LS is an effective tool for the diagnosis of orthopedic infection in horses.

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KW - Infection

KW - Leukocyte

KW - Scintigraphy

KW - Tc-HMPAO

KW - Technetium-99m

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Scintigraphic detection of equine orthopedic infection using Tc-HMPAO labeled leukocytes in 14 horses

Abstract

Keywords

ASJC Scopus subject areas

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