Scanned-beam assisted mild tumor heating using a dual-functional ultrasound linear array

Chun Yen Lai; Dustin E. Kruse; Charles F. Caskey; Douglas N. Stephens; Patrick L. Sutcliffe; Katherine W. Ferrara

doi:10.1109/ULTSYM.2009.5441776

Scanned-beam assisted mild tumor heating using a dual-functional ultrasound linear array

Chun Yen Lai, Dustin E. Kruse, Charles F. Caskey, Douglas N. Stephens, Patrick L. Sutcliffe, Katherine W. Ferrara

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

A commercial ultrasound scanner, a customized co-linear array ultrasound transducer and a real-time temperature feedback controller have been combined to generate controlled mild hyperthermia. Previous studies have shown that single beam-based image-guided local drug delivery can improve the treatment of small tumors. In this study, a scanned-beam based insonation mode was developed to achieve uniform therapy over a larger region. A color-region of interest (ROI) was used to define the scanned area, while periodic B-mode imaging was used to visualize the tumor. In this study, a thermal strain algorithm was also examined for temperature estimation and this algorithm will be applied for temperature control in the future.

Original language	English (US)
Title of host publication	Proceedings - IEEE Ultrasonics Symposium
DOIs	https://doi.org/10.1109/ULTSYM.2009.5441776
State	Published - 2009
Event	2009 IEEE International Ultrasonics Symposium, IUS 2009 - Rome, Italy Duration: Sep 20 2009 → Sep 23 2009

Other

Other	2009 IEEE International Ultrasonics Symposium, IUS 2009
Country	Italy
City	Rome
Period	9/20/09 → 9/23/09

Keywords

Mild hyperthermia
Thermal strain
Tissue heating
Ultrasound

ASJC Scopus subject areas

Acoustics and Ultrasonics

Access to Document

10.1109/ULTSYM.2009.5441776

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Cite this

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title = "Scanned-beam assisted mild tumor heating using a dual-functional ultrasound linear array",

abstract = "A commercial ultrasound scanner, a customized co-linear array ultrasound transducer and a real-time temperature feedback controller have been combined to generate controlled mild hyperthermia. Previous studies have shown that single beam-based image-guided local drug delivery can improve the treatment of small tumors. In this study, a scanned-beam based insonation mode was developed to achieve uniform therapy over a larger region. A color-region of interest (ROI) was used to define the scanned area, while periodic B-mode imaging was used to visualize the tumor. In this study, a thermal strain algorithm was also examined for temperature estimation and this algorithm will be applied for temperature control in the future.",

keywords = "Mild hyperthermia, Thermal strain, Tissue heating, Ultrasound",

author = "Lai, {Chun Yen} and Kruse, {Dustin E.} and Caskey, {Charles F.} and Stephens, {Douglas N.} and Sutcliffe, {Patrick L.} and Ferrara, {Katherine W.}",

year = "2009",

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language = "English (US)",

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AU - Caskey, Charles F.

AU - Stephens, Douglas N.

AU - Sutcliffe, Patrick L.

AU - Ferrara, Katherine W.

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AB - A commercial ultrasound scanner, a customized co-linear array ultrasound transducer and a real-time temperature feedback controller have been combined to generate controlled mild hyperthermia. Previous studies have shown that single beam-based image-guided local drug delivery can improve the treatment of small tumors. In this study, a scanned-beam based insonation mode was developed to achieve uniform therapy over a larger region. A color-region of interest (ROI) was used to define the scanned area, while periodic B-mode imaging was used to visualize the tumor. In this study, a thermal strain algorithm was also examined for temperature estimation and this algorithm will be applied for temperature control in the future.

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