Sarcopenia in rheumatic disorders: what the radiologist and rheumatologist should know

Wilfred Manzano, Leon Lenchik, Akshay S. Chaudhari, Lawrence Yao, Sarthak Gupta, Robert D. Boutin

Research output: Contribution to journalReview articlepeer-review

Abstract

Sarcopenia is defined as the loss of muscle mass, strength, and function. Increasing evidence shows that sarcopenia is common in patients with rheumatic disorders. Although sarcopenia can be diagnosed using bioelectrical impedance analysis or DXA, increasingly it is diagnosed using CT, MRI, and ultrasound. In rheumatic patients, CT and MRI allow “opportunistic” measurement of body composition, including surrogate markers of sarcopenia, from studies obtained during routine patient care. Recognition of sarcopenia is important in rheumatic patients because sarcopenia can be associated with disease progression and poor outcomes. This article reviews how opportunistic evaluation of sarcopenia in rheumatic patients can be accomplished and potentially contribute to improved patient care.

Original languageEnglish (US)
JournalSkeletal Radiology
DOIs
StateAccepted/In press - 2021
Externally publishedYes

Keywords

  • Frailty
  • Muscle
  • Myosteatosis
  • Opportunistic imaging
  • Rheumatology
  • Sarcopenia

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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