Salmonella typhimurium IroN and FepA proteins mediate uptake of enterobactin but differ in their specificity for other siderophores

Wolfgang Rabsch, Wolfgang Voigt, Rolf Reissbrodt, Renee M Tsolis, Andreas J Baumler

Research output: Contribution to journalArticle

56 Scopus citations

Abstract

Salmonella typhimurium possesses two outer membrane receptor proteins, Iron and FepA, which have been implicated in the uptake of enterobactin. To determine whether both receptors have identical substrate specificities, fepA and iron mutants and a double mutant were characterized. While both receptors transported enterobactin, the uptake of corynebactin and myxochelin C was selectively mediated by Iron and FepA, respectively.

Original languageEnglish (US)
Pages (from-to)3610-3612
Number of pages3
JournalJournal of Bacteriology
Volume181
Issue number11
StatePublished - Jun 1999
Externally publishedYes

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Immunology

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