TY - JOUR
T1 - Salmonella, the host and its microbiota
AU - Thiennimitr, Parameth
AU - Winter, Sebastian E.
AU - Baumler, Andreas J
PY - 2012/2
Y1 - 2012/2
N2 - The intestine is host to a diverse bacterial community whose structure, at the phylum level, is maintained through unknown mechanisms. Acute inflammation triggered by enteric pathogens, such as Salmonella enterica serotype Typhimurium (S. Typhimurium), is accompanied by changes in the bacterial community structure marked by an outgrowth of the pathogen. Recent studies show that S. Typhimurium can harness benefit from the host response to edge out the beneficial bacterial species that dominate in the healthy gut. The elucidation of how S. Typhimurium alters the bacterial community structure during gastroenteritis is beginning to provide insights into mechanisms that dictate the balance between the host and its microbiota.
AB - The intestine is host to a diverse bacterial community whose structure, at the phylum level, is maintained through unknown mechanisms. Acute inflammation triggered by enteric pathogens, such as Salmonella enterica serotype Typhimurium (S. Typhimurium), is accompanied by changes in the bacterial community structure marked by an outgrowth of the pathogen. Recent studies show that S. Typhimurium can harness benefit from the host response to edge out the beneficial bacterial species that dominate in the healthy gut. The elucidation of how S. Typhimurium alters the bacterial community structure during gastroenteritis is beginning to provide insights into mechanisms that dictate the balance between the host and its microbiota.
UR - http://www.scopus.com/inward/record.url?scp=84856083725&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84856083725&partnerID=8YFLogxK
U2 - 10.1016/j.mib.2011.10.002
DO - 10.1016/j.mib.2011.10.002
M3 - Article
C2 - 22030447
AN - SCOPUS:84856083725
VL - 15
SP - 108
EP - 114
JO - Current Opinion in Microbiology
JF - Current Opinion in Microbiology
SN - 1369-5274
IS - 1
ER -