Salmonella, the host and its microbiota

Parameth Thiennimitr, Sebastian E. Winter, Andreas J Baumler

Research output: Contribution to journalArticle

64 Scopus citations

Abstract

The intestine is host to a diverse bacterial community whose structure, at the phylum level, is maintained through unknown mechanisms. Acute inflammation triggered by enteric pathogens, such as Salmonella enterica serotype Typhimurium (S. Typhimurium), is accompanied by changes in the bacterial community structure marked by an outgrowth of the pathogen. Recent studies show that S. Typhimurium can harness benefit from the host response to edge out the beneficial bacterial species that dominate in the healthy gut. The elucidation of how S. Typhimurium alters the bacterial community structure during gastroenteritis is beginning to provide insights into mechanisms that dictate the balance between the host and its microbiota.

Original languageEnglish (US)
Pages (from-to)108-114
Number of pages7
JournalCurrent Opinion in Microbiology
Volume15
Issue number1
DOIs
StatePublished - Feb 2012

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)
  • Microbiology

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