Salivary alpha-amylase as a stress biomarker in diseased dogs

Hwa Ran Hong, Ye In Oh, Young Jun Kim, Kyoung Won Seo

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Salivary alpha-amylase (sAA) is a stress biomarker in human diseases, but there are no reports of sAA measurements in diseased dogs. This study measured the sAA and serum alpha-amylase (AA) levels in 16 healthy dogs and 31 diseased dogs using a kinetic enzyme assay to assess the stress status. The sAA and serum AA levels were significantly higher in the diseased dogs than in healthy dogs (p < 0.05), but there was no correlation between the 2 groups (r = 0.251, p = 0.089). This suggests that sAA can be useful as a stress biomarker in diseased dogs.

Original languageEnglish (US)
Article numbere46
JournalJournal of Veterinary Science
Issue number5
StatePublished - Jan 1 2019
Externally publishedYes


  • Alpha-amylase
  • Dogs
  • Saliva
  • Serum
  • Stress

ASJC Scopus subject areas

  • veterinary(all)


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