Abstract
Intracytoplasmic sperm injection (ICSI) is an important assisted reproductive technology (ART). Due to deployment difficulties and low efficiency of the earlier (conventional) version of ICSI, especially in the mouse, a piezo-assisted ICSI technique had evolved as a popular ART methodology in recent years. An important and remaining problem with this technique, however, is that it requires small amounts of mercury to stabilize the pipette tip when piezoelectric force pulses are applied. To eliminate this problem we developed and tested a completely different and mercury-free technology, called the "Ros-Drill
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1744-1751 |
| Number of pages | 8 |
| Journal | Molecular Reproduction and Development |
| Volume | 75 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 2008 |
Keywords
- Assisted reproduction
- ICSI
- Microinjection
- Micromanipulation
ASJC Scopus subject areas
- Genetics
- Developmental Biology
- Cell Biology
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Cite this
Ergenc, A. F., Li, M. W., Toner, M., Biggers, J. D., Lloyd, K. C. K., & Olgac, N. (2008). Rotationally oscillating drill (Ros-Drill©) for mouse ICSI without using mercury. Molecular Reproduction and Development, 75(12), 1744-1751. https://doi.org/10.1002/mrd.20919