Abstract
Growth of yeast in the presence of the protein synthesis inhibitors cycloheximide and cryptopleurine results in elimination ("curing") of the cytoplasmically-inherited killer virus. Yeast mutants with ribosomal subunits resistant to the translational effects of one of these antibiotics are specifically resistant to curing by that antibiotic, indicating that these substances act on the virus by their effect on protein synthesis.
Original language | English (US) |
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Pages (from-to) | 161-163 |
Number of pages | 3 |
Journal | Current Genetics |
Volume | 5 |
Issue number | 2 |
DOIs | |
State | Published - Jul 1982 |
Externally published | Yes |
Keywords
- Cryptopleurine
- Cycloheximide
- Killer virus
ASJC Scopus subject areas
- Genetics