Role of protein synthesis in the replication of the killer virus of yeast

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Growth of yeast in the presence of the protein synthesis inhibitors cycloheximide and cryptopleurine results in elimination ("curing") of the cytoplasmically-inherited killer virus. Yeast mutants with ribosomal subunits resistant to the translational effects of one of these antibiotics are specifically resistant to curing by that antibiotic, indicating that these substances act on the virus by their effect on protein synthesis.

Original languageEnglish (US)
Pages (from-to)161-163
Number of pages3
JournalCurrent Genetics
Issue number2
StatePublished - Jul 1982
Externally publishedYes



  • Cryptopleurine
  • Cycloheximide
  • Killer virus

ASJC Scopus subject areas

  • Genetics

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