Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome

Sridevi Devaraj, Simona Valleggi, David Siegel, Ishwarlal Jialal

Research output: Contribution to journalArticle

48 Scopus citations

Abstract

Metabolic syndrome is associated with increased propensity for diabetes and cardiovascular disease. Lowgrade inflammation is characteristic of metabolic syndrome. C-reactive protein, the best characterized biomarker of inflammation, is also an independent predictor of future cardiovascular events. This review outlines the role of highsensitivityC-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome by inducing endothelial cell dysfunction and activating monocytes.

Original languageEnglish (US)
Pages (from-to)110-118
Number of pages9
JournalCurrent Atherosclerosis Reports
Volume12
Issue number2
DOIs
StatePublished - Mar 2010
Externally publishedYes

Keywords

  • Cardiovascular risk
  • CRP
  • Inflammation
  • Metabolic syndrome

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Medicine(all)

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