RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes.

C. Duncan, P. A. Biro, Prabhakara V Choudary, J. T. Elder, R. R. Wang, B. G. Forget, J. K. de Riel, S. M. Weissman

Research output: Contribution to journalArticle

96 Scopus citations

Abstract

Cloned human DNA fragments containing globin genes are transcribed in vitro to form discrete RNA species. One transcription unit is located approximately 1500 base pairs upstream from the G-gamma-globin gene. This transcript is partially homologous to a polymerase III template located approximately 1000 base pairs upstream from the delta-globin gene and to DNA located a short distance downstream from the beta-globin gene.

Original languageEnglish (US)
Pages (from-to)5095-5099
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume76
Issue number10
StatePublished - Oct 1979
Externally publishedYes

ASJC Scopus subject areas

  • General
  • Genetics

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    Duncan, C., Biro, P. A., Choudary, P. V., Elder, J. T., Wang, R. R., Forget, B. G., de Riel, J. K., & Weissman, S. M. (1979). RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes. Proceedings of the National Academy of Sciences of the United States of America, 76(10), 5095-5099.