Risk factors for systemic illnesses following agricultural exposures to restricted organophosphates in California, 1984-1988

Zipora Weinbaum, Marc B Schenker, Ellen B Gold, Steven J. Samuels, Michael A. O'Malley

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Organophosphate (OP)-related systemic illnesses reported to the Worker Health and Safety (WH and S) Branch, and restricted OP-related agricultural use data reported to the Information Services Branch at the California Department of Food and Agriculture (CDFA) (now CAL-EPA) during 1984-1988 were used to assess factors associated with OP-related systemic illnesses. Counts of OP-related systemic illnesses (numerator), relative to OP-related use data (denominator), such as pounds applied, number of applications, and acres treated (pounds applied/acres treated), were analyzed by crop treated, season of application, method of application, geographic region, and by specific OP applied. A Relative Illness/Use Ratio (RIUR) was calculated by Poisson regression. The highest risk of systemic illness was associated with OP applications to fleshy fruit (mainly fruit trees) compared to all other crops combined (RIUR = 2.9, 95%CI = 2.2-3.9) using pounds applied in the denominator, followed by vegetables and melons (RIUR = 1.9, 95%CI = 1.4- 2.4). Air applications resulted in higher RIURs for systemic illness than did ground applications (RIUR = 2.1, 95%CI = 1.7-2.5). Specific OPs that showed significantly elevated RIURs for systemic illness when compared to other OPs were Mevinphos (RIUR = 5.8, 95%CI = 5.0-6.8), Demeton (RIUR = 4.3, 95%CI = 2.6-7.1). Oxydemeton-Methyl (RIUR = 3.8, 95%CI = 3.0-4.9), Methamidophos (RIUR = 1.6, 95%CI = 1.2-2.0) and Azinphos-Methyl (RIUR = 1.3, 95%CI = 1.1- 1.6).

Original languageEnglish (US)
Pages (from-to)572-579
Number of pages8
JournalAmerican Journal of Industrial Medicine
Volume31
Issue number5
DOIs
StatePublished - 1997

Fingerprint

Organophosphates
Mevinphos
Fruit
Disulfoton
Azinphosmethyl
Cucurbitaceae
Information Services
Agriculture
Vegetables
Air
Safety
Food
Health

Keywords

  • agriculture
  • farming
  • organophosphates
  • pesticides

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Risk factors for systemic illnesses following agricultural exposures to restricted organophosphates in California, 1984-1988. / Weinbaum, Zipora; Schenker, Marc B; Gold, Ellen B; Samuels, Steven J.; O'Malley, Michael A.

In: American Journal of Industrial Medicine, Vol. 31, No. 5, 1997, p. 572-579.

Research output: Contribution to journalArticle

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abstract = "Organophosphate (OP)-related systemic illnesses reported to the Worker Health and Safety (WH and S) Branch, and restricted OP-related agricultural use data reported to the Information Services Branch at the California Department of Food and Agriculture (CDFA) (now CAL-EPA) during 1984-1988 were used to assess factors associated with OP-related systemic illnesses. Counts of OP-related systemic illnesses (numerator), relative to OP-related use data (denominator), such as pounds applied, number of applications, and acres treated (pounds applied/acres treated), were analyzed by crop treated, season of application, method of application, geographic region, and by specific OP applied. A Relative Illness/Use Ratio (RIUR) was calculated by Poisson regression. The highest risk of systemic illness was associated with OP applications to fleshy fruit (mainly fruit trees) compared to all other crops combined (RIUR = 2.9, 95{\%}CI = 2.2-3.9) using pounds applied in the denominator, followed by vegetables and melons (RIUR = 1.9, 95{\%}CI = 1.4- 2.4). Air applications resulted in higher RIURs for systemic illness than did ground applications (RIUR = 2.1, 95{\%}CI = 1.7-2.5). Specific OPs that showed significantly elevated RIURs for systemic illness when compared to other OPs were Mevinphos (RIUR = 5.8, 95{\%}CI = 5.0-6.8), Demeton (RIUR = 4.3, 95{\%}CI = 2.6-7.1). Oxydemeton-Methyl (RIUR = 3.8, 95{\%}CI = 3.0-4.9), Methamidophos (RIUR = 1.6, 95{\%}CI = 1.2-2.0) and Azinphos-Methyl (RIUR = 1.3, 95{\%}CI = 1.1- 1.6).",
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