TY - JOUR
T1 - Risk factors for childhood respiratory disease. Analysis of pulmonary function
AU - Vedal, S.
AU - Schenker, Marc B
AU - Samet, J. M.
AU - Speizer, F. E.
PY - 1984
Y1 - 1984
N2 - Four thousand elementary-school-age children from a rural area of western Pennsylvania participated in a cross-sectional survey that consisted of a standardized respiratory questionnaire completed by their parents and spirometric testing at school. Spirographic tracings were digitized to obtain the FVC, FEV0.75, FEF25-75, V̇max75, and V̇max90, which were standardized for height, age, and sex for the subsequent analyses. Independent associations' of potential risk factors with the standardized pulmonary function measures were evaluated with multiple regression techniques. Asthma, persistent wheeze, and parental smoking habits, especially those of the mothers, were associated with lower flow rates. The effect of parental smoking was primarly due to smoking by the mother and was stronger in girls. In female children of currently smoking mothers, FEF25-75 was 96% of predicted, V̇max75 was 95% of predicted, and V̇max90 was 92% of predicted; each flow measure was 98% of predicted in male children of smoking mothers. Prolonged hospitalization at birth was independently associated with lower FEV0.75 and flow rates. Low socioeconomic status was associated with lower FVC and FEV0.75. Neither current gas stove use nor a history of severe chest illness before 2 yr of age were independently associated with lower levels of pulmonary function.
AB - Four thousand elementary-school-age children from a rural area of western Pennsylvania participated in a cross-sectional survey that consisted of a standardized respiratory questionnaire completed by their parents and spirometric testing at school. Spirographic tracings were digitized to obtain the FVC, FEV0.75, FEF25-75, V̇max75, and V̇max90, which were standardized for height, age, and sex for the subsequent analyses. Independent associations' of potential risk factors with the standardized pulmonary function measures were evaluated with multiple regression techniques. Asthma, persistent wheeze, and parental smoking habits, especially those of the mothers, were associated with lower flow rates. The effect of parental smoking was primarly due to smoking by the mother and was stronger in girls. In female children of currently smoking mothers, FEF25-75 was 96% of predicted, V̇max75 was 95% of predicted, and V̇max90 was 92% of predicted; each flow measure was 98% of predicted in male children of smoking mothers. Prolonged hospitalization at birth was independently associated with lower FEV0.75 and flow rates. Low socioeconomic status was associated with lower FVC and FEV0.75. Neither current gas stove use nor a history of severe chest illness before 2 yr of age were independently associated with lower levels of pulmonary function.
UR - http://www.scopus.com/inward/record.url?scp=0021222962&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021222962&partnerID=8YFLogxK
M3 - Article
C2 - 6465673
AN - SCOPUS:0021222962
VL - 130
SP - 187
EP - 192
JO - American Journal of Respiratory and Critical Care Medicine
JF - American Journal of Respiratory and Critical Care Medicine
SN - 1073-449X
IS - 2
ER -