Risk factors associated with outcome in dogs with tetanus

38 Cases (1987-2005)

Jamie Burkitt Creedon, Beverly Sturges, Karl Jandrey, Philip H Kass

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Objective - To assess the clinical course of disease and risk factors associated with outcome in dogs with tetanus. Design - Retrospective case series. Animals - 38 dogs with tetanus. Procedures - Data were collected from medical records of dogs with tetanus, including signalment; wound characteristics; initial clinical signs; severity of worst clinical signs; time to wound management, antimicrobial treatment, and antitoxin administration; and 28-day survival rate. Statistical analyses were performed to evaluate relationships between the potentially predictive variables and disease progression and outcome. Results - The 28-day survival rate was 77% (among 35 uncensored dogs). The most common initial clinical signs in affected dogs were ocular (n = 18) and facial (11) abnormalities. Nineteen dogs progressed to recumbency with severe muscle spasms, and 14 dogs had high or low heart rate or blood pressure values. Eight dogs died or were euthanized because of complications of tetanus. There was a significant association between younger age and development of more severe clinical signs. Furthermore, a significant inverse relationship between development of severe clinical signs and survival was identified. There was no association between earlier initiation of wound management, antimicrobial administration, or antitoxin administration and either progression of signs or 28-day survival rate. Wound type was not associated with 28-day survival rate. Conclusions and Clinical Relevance - Results suggest that younger dogs with tetanus may be more likely to develop severe clinical signs. The prognosis for survival in dogs with tetanus is good if abnormalities in heart rate or blood pressure values do not develop.

Original languageEnglish (US)
Pages (from-to)76-83
Number of pages8
JournalJournal of the American Veterinary Medical Association
Volume230
Issue number1
DOIs
StatePublished - Jan 1 2007

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tetanus
Tetanus
risk factors
Dogs
dogs
animal injuries
survival rate
antitoxins
Antitoxins
Wounds and Injuries
disease course
blood pressure
heart rate
anti-infective agents
Heart Rate
Blood Pressure
Spasm
prognosis
Medical Records
Disease Progression

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Risk factors associated with outcome in dogs with tetanus : 38 Cases (1987-2005). / Burkitt Creedon, Jamie; Sturges, Beverly; Jandrey, Karl; Kass, Philip H.

In: Journal of the American Veterinary Medical Association, Vol. 230, No. 1, 01.01.2007, p. 76-83.

Research output: Contribution to journalArticle

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