TY - JOUR
T1 - Risk factors associated with human brucellosis in the country of Georgia
T2 - A case-control study
AU - Havas, K. A.
AU - Ramishvili, M.
AU - Navdarashvili, A.
AU - Hill, Ashley E
AU - Tsanava, S.
AU - Imnadze, P.
AU - Salman, M. D.
PY - 2013/1
Y1 - 2013/1
N2 - SUMMARY Human brucellosis occurs when humans ingest or contact Brucella spp. from shedding animals or contaminated environments and food. In Georgia animal and human brucellosis is endemic, but the epidemiology has not been fully characterized. A case-control study was conducted in 2010 to identify risk factors for human brucellosis. Using multivariable logistic regression, the following risk factors were identified: animal-related work [odds ratio (OR) 77·8, 90% confidence interval (CI) 4·7-1278], non-animal-related work (OR 12·7, 90% CI 1·1-149), being unemployed or a pensioner (OR 13·1, 90% CI 1·7, 101), sheep ownership (OR 19·3, 90% CI 5·1-72·6), making dairy products (OR 12·4, 90% CI 1·4-113), living in eastern Georgia (Kakheti) (OR 278·1, 90% CI 9·5-8100), and being aged >44 years (OR 9·3, 90% CI 1·02-84·4). Education of at-risk groups about risk factors and control of disease in sheep may reduce the human disease risk. This is the first study of its kind in Georgia since the collapse of the Soviet Union.
AB - SUMMARY Human brucellosis occurs when humans ingest or contact Brucella spp. from shedding animals or contaminated environments and food. In Georgia animal and human brucellosis is endemic, but the epidemiology has not been fully characterized. A case-control study was conducted in 2010 to identify risk factors for human brucellosis. Using multivariable logistic regression, the following risk factors were identified: animal-related work [odds ratio (OR) 77·8, 90% confidence interval (CI) 4·7-1278], non-animal-related work (OR 12·7, 90% CI 1·1-149), being unemployed or a pensioner (OR 13·1, 90% CI 1·7, 101), sheep ownership (OR 19·3, 90% CI 5·1-72·6), making dairy products (OR 12·4, 90% CI 1·4-113), living in eastern Georgia (Kakheti) (OR 278·1, 90% CI 9·5-8100), and being aged >44 years (OR 9·3, 90% CI 1·02-84·4). Education of at-risk groups about risk factors and control of disease in sheep may reduce the human disease risk. This is the first study of its kind in Georgia since the collapse of the Soviet Union.
KW - Animal pathogens
KW - Brucella
KW - brucellosis
KW - zoonoses
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U2 - 10.1017/S0950268812000313
DO - 10.1017/S0950268812000313
M3 - Article
C2 - 22404868
AN - SCOPUS:84870914485
VL - 141
SP - 45
EP - 53
JO - Journal of Hygiene
JF - Journal of Hygiene
SN - 0950-2688
IS - 1
ER -