Risk factors associated with Corynebacterium pseudotuberculosis infection in California horses

M. G. Doherr, Tim Carpenter, K. M P Hanson, William D Wilson, Ian Gardner

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

A case-control study was designed using equine medical records from the UC Davis Veterinary Medical Teaching Hospital (VMTH) and data derived through a mailed survey. The objective was to evaluate the associations between horse demographics, horse-management factors, and equine Corynebacterium pseudotuberculosis infection in California. Horses admitted to the VMTH between July 1 1992 and June 30 1994 served as the study base for case identification and simple random sampling of 800 controls. A questionnaire was mailed to the owners of all horses enrolled in the study to collect data on demographics, management and health-related questions. A logistic-regression model containing age, outdoor activity level, other locations in California, insect-control measures, contact with other horses, and summer pasture was developed. The final model was adjusted for the suspected confounding variables admission type, regular teaching hospital patient and breed. Horses of age between 1 and 2 yrs and between 3 and 5 yrs, and horses in contact with other horses or horses on summer pasture had significantly increased odds (p<0.05) of being diagnosed with C. pseudotuberculosis infection. The results support the hypotheses that the disease predominantly affects young-adult horses of all breeds and both sexes, and that management factors play an important role in occurrence of the disease. Since the existing serological test system is not reliable and destruction of infected animals is not feasible, the most-logical approach for disease prevention is the early identification and isolation of clinical cases and the implementation of management changes like improvement of stable hygiene and insect control and change of pasture practices.

Original languageEnglish (US)
Pages (from-to)229-239
Number of pages11
JournalPreventive Veterinary Medicine
Volume35
Issue number4
StatePublished - Jun 30 1998

Fingerprint

Corynebacterium Infections
Corynebacterium pseudotuberculosis
Horses
risk factors
horses
infection
Teaching Hospitals
Insect Control
insect control
pastures
Case-Control Studies
demographic statistics
Logistic Models
Demography
breeds
Sex Factors
Confounding Factors (Epidemiology)
disease occurrence
summer
disease prevention

Keywords

  • Case-control study
  • Corynebacterium pseudotuberculosis
  • Horse
  • Logistic regression
  • Modelling
  • Retrospective study

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Risk factors associated with Corynebacterium pseudotuberculosis infection in California horses. / Doherr, M. G.; Carpenter, Tim; Hanson, K. M P; Wilson, William D; Gardner, Ian.

In: Preventive Veterinary Medicine, Vol. 35, No. 4, 30.06.1998, p. 229-239.

Research output: Contribution to journalArticle

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