Right and left lung perfusion: In vitro and in vivo validation with oblique-angle, velocity-encoded cine MR imaging

Gary R. Caputo, Chisato Kondo, Takayuki Masui, Salvatore J. Geraci, Elyse Foster, Margaret M. O'Sullivan, Charles B. Higgins

Research output: Contribution to journalArticle

120 Scopus citations

Abstract

Quantification of pulmonary flow is clinically important in the evaluation of both congenital and acquired heart disease. Velocity-encoded cine magnetic resonance (MR) is a promising technique for measuring velocity and volume of blood flow. The authors report validation of the accuracy of velocity-encoded cine MR for measurement of oblique-angle flow in vitro, with use of a constant-flow phantom, and in vivo, with nine healthy volunteers in whom velocities were measured separately in the main, right, and left pulmonary arteries. Findings at MR were compared with findings at Doppler echocardiography. Velocity measurements in a flow phantom with cine MR correlated well with direct measurements at Doppler echocardiography. Velocity-encoded cine MR enabled accurate and reproducible measurement of absolute blood flow in healthy subjects. Oblique-gradient flow encoding (ie, flow-encoding direction coinciding with the true direction of flow) was the method of choice for velocity measurements in the right and left pulmonary arteries.

Original languageEnglish (US)
Pages (from-to)693-698
Number of pages6
JournalRadiology
Volume180
Issue number3
StatePublished - Sep 1991

Keywords

  • Blood, flow dynamics, 60.919
  • Lung, MR studies, 60.1214, 60.1296
  • Lung, perfusion
  • Lung, US studies, 60.1298, 60.12984

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

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    Caputo, G. R., Kondo, C., Masui, T., Geraci, S. J., Foster, E., O'Sullivan, M. M., & Higgins, C. B. (1991). Right and left lung perfusion: In vitro and in vivo validation with oblique-angle, velocity-encoded cine MR imaging. Radiology, 180(3), 693-698.