Rhodococcus equi Pneumonia: Clinical Findings, Diagnosis, Treatment and Prevention

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Rhodococcus equi is a Gram-positive facultative intracellular bacterial pathogen and the most common cause of severe infectious pneumonia in foals. The pathogen is ubiquitous in the environment, but becomes concentrated in breeding farm situations due to its ability to reproduce in the gastrointestinal tract of herbivores. Foals may be exposed to the organism soon after birth; overt infection results in variable number of foals due to a combination of pathogen virulence, host susceptibility, and infective dose of the organism. Herd health programs using passive transfer of antibodies, especially with transfusions of equine hyperimmune plasma, can decrease incidence rates on affected premises, but rarely prevent infection in all susceptible individuals. An effective vaccine is not currently available. Combined therapy of clinically affected individuals using macrolide antibiotics combined with rifampin has improved outcome, including both morbidity and mortality.

Original languageEnglish (US)
Pages (from-to)203-210
Number of pages8
JournalClinical Techniques in Equine Practice
Volume5
Issue number3
DOIs
StatePublished - Sep 2006

Fingerprint

Rhodococcus equi
foals
pneumonia
Pneumonia
Herbivory
Aptitude
Passive Immunization
pathogens
Macrolides
Rifampin
Infection
macrolide antibiotics
Horses
Breeding
Virulence
Gastrointestinal Tract
herd health
rifampicin
Vaccines
organisms

Keywords

  • herd health
  • pneumonia
  • Rhodococcus equi
  • virulence associated plasmid

ASJC Scopus subject areas

  • Equine

Cite this

Rhodococcus equi Pneumonia : Clinical Findings, Diagnosis, Treatment and Prevention. / Heidmann, Peter; Madigan, John E; Watson, Johanna L.

In: Clinical Techniques in Equine Practice, Vol. 5, No. 3, 09.2006, p. 203-210.

Research output: Contribution to journalArticle

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