Rhinal-hippocampal information flow reverses between memory encoding and retrieval

Juergen Fell, Tobias Wagner, Bernhard P. Staresina, Charan Ranganath, Christian E. Elger, Nikolai Axmacher

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The medial temporal lobe is crucial for the encoding and retrieval of episodic long-term memories. It is widely assumed that memory encoding is associated with information transfer from sensory regions via the rhinal cortex into the hippocampus. Retrieval of information should then be associated with transfer in the reverse direction. However, experimental evidence for this mechanism is still lacking. Here, we show in human intracranial EEG data during two independent recognition memory paradigms that rhinal-hippocampal information flow significantly changes its directionality from encoding to retrieval. Using a novel phase-based method to analyze directional coupling of oscillations, coupling values were more positive (i.e., from rhinal cortex to the hippocampus) during encoding as compared to retrieval. These effects were observed in the delta (1–3 Hz) range where rhinal-hippocampal post-stimulus phase synchronization increased most robustly across both experiments.

Original languageEnglish (US)
Title of host publicationNeural Information Processing - 23rd International Conference, ICONIP 2016, Proceedings
PublisherSpringer Verlag
Pages105-114
Number of pages10
Volume9947 LNCS
ISBN (Print)9783319466866
DOIs
StatePublished - 2016
Event23rd International Conference on Neural Information Processing, ICONIP 2016 - Kyoto, Japan
Duration: Oct 16 2016Oct 21 2016

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume9947 LNCS
ISSN (Print)03029743
ISSN (Electronic)16113349

Other

Other23rd International Conference on Neural Information Processing, ICONIP 2016
CountryJapan
CityKyoto
Period10/16/1610/21/16

Fingerprint

Information Flow
Reverse
Retrieval
Encoding
Data storage equipment
Hippocampus
Cortex
Electroencephalography
Phase Synchronization
Information Transfer
Memory Term
Synchronization
Paradigm
Oscillation
Experiments
Range of data
Experiment

Keywords

  • Directional coupling
  • Hippocampus
  • Intracranial EEG
  • Long-term memory
  • Medial temporal lobe
  • Rhinal cortex

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

Cite this

Fell, J., Wagner, T., Staresina, B. P., Ranganath, C., Elger, C. E., & Axmacher, N. (2016). Rhinal-hippocampal information flow reverses between memory encoding and retrieval. In Neural Information Processing - 23rd International Conference, ICONIP 2016, Proceedings (Vol. 9947 LNCS, pp. 105-114). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 9947 LNCS). Springer Verlag. https://doi.org/10.1007/978-3-319-46687-3_11

Rhinal-hippocampal information flow reverses between memory encoding and retrieval. / Fell, Juergen; Wagner, Tobias; Staresina, Bernhard P.; Ranganath, Charan; Elger, Christian E.; Axmacher, Nikolai.

Neural Information Processing - 23rd International Conference, ICONIP 2016, Proceedings. Vol. 9947 LNCS Springer Verlag, 2016. p. 105-114 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 9947 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fell, J, Wagner, T, Staresina, BP, Ranganath, C, Elger, CE & Axmacher, N 2016, Rhinal-hippocampal information flow reverses between memory encoding and retrieval. in Neural Information Processing - 23rd International Conference, ICONIP 2016, Proceedings. vol. 9947 LNCS, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 9947 LNCS, Springer Verlag, pp. 105-114, 23rd International Conference on Neural Information Processing, ICONIP 2016, Kyoto, Japan, 10/16/16. https://doi.org/10.1007/978-3-319-46687-3_11
Fell J, Wagner T, Staresina BP, Ranganath C, Elger CE, Axmacher N. Rhinal-hippocampal information flow reverses between memory encoding and retrieval. In Neural Information Processing - 23rd International Conference, ICONIP 2016, Proceedings. Vol. 9947 LNCS. Springer Verlag. 2016. p. 105-114. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)). https://doi.org/10.1007/978-3-319-46687-3_11
Fell, Juergen ; Wagner, Tobias ; Staresina, Bernhard P. ; Ranganath, Charan ; Elger, Christian E. ; Axmacher, Nikolai. / Rhinal-hippocampal information flow reverses between memory encoding and retrieval. Neural Information Processing - 23rd International Conference, ICONIP 2016, Proceedings. Vol. 9947 LNCS Springer Verlag, 2016. pp. 105-114 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).
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