Rheumatologic manifestations of primary immunodeficiency diseases

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

In the last 5 years, several hundred articles have been published concerning the link between primary immunodeficiency disease (PID) and rheumatologic diseases. Although rheumatologic complications were originally thought to be at the opposite ends of the spectrum of immunopathologic manifestations, they are now all being considered secondary manifestations of a causative primary “immune derangement.” For the rheumatologist, it is important to be able to identify patients who may present with typical rheumatologic findings but who have an underlying PID. In a systematic manner, this overview addresses both the systemic and organ-based rheumatologic diseases which have known associations with primary immunodeficiencies, and explores how immunodeficiency may actually cause these clinical manifestations.

Original languageEnglish (US)
Pages (from-to)843-850
Number of pages8
JournalClinical Rheumatology
Volume35
Issue number4
DOIs
StatePublished - Apr 1 2016
Externally publishedYes

Keywords

  • Autoimmunity
  • Immunodeficiency
  • Rheumatologic disease

ASJC Scopus subject areas

  • Rheumatology

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