Abstract
Rheumatoid arthritis (RA) is a potentially destructive disease with profound impact on patients' function and quality of life. Newer therapeutic agents have revolutionized outcomes but have not resulted in best outcomes for all patients. However, RA is a heterogeneous disease comprising several subsets of patients with variations in pathogenesis. Elucidation of these differences and its molecular mechanisms may lead to better therapeutic approaches. To treat patients with RA more effectively, it is essential to intervene in the earliest events of the pathophysiologic processes of this disease. In this chapter, we will present the latest advances in the understanding of the disease process of RA and its clinical relevance.
Original language | English (US) |
---|---|
Title of host publication | Inflammation, Advancing Age and Nutrition: Research and Clinical Interventions |
Publisher | Elsevier Inc. |
Pages | 215-229 |
Number of pages | 15 |
ISBN (Print) | 9780123978035 |
DOIs | |
State | Published - Oct 2013 |
Keywords
- Chronic inflammatory diseases
- Immune-based therapy
- Immunopathogenesis
- Rheumatoid arthritis
ASJC Scopus subject areas
- Medicine(all)
- Dentistry(all)