Abstract
Rheumatoid arthritis (RA) is a potentially destructive disease with profound impact on patients' function and quality of life. Newer therapeutic agents have revolutionized outcomes but have not resulted in best outcomes for all patients. However, RA is a heterogeneous disease comprising several subsets of patients with variations in pathogenesis. Elucidation of these differences and its molecular mechanisms may lead to better therapeutic approaches. To treat patients with RA more effectively, it is essential to intervene in the earliest events of the pathophysiologic processes of this disease. In this chapter, we will present the latest advances in the understanding of the disease process of RA and its clinical relevance.
| Original language | English (US) |
|---|---|
| Title of host publication | Inflammation, Advancing Age and Nutrition: Research and Clinical Interventions |
| Publisher | Elsevier Inc. |
| Pages | 215-229 |
| Number of pages | 15 |
| ISBN (Print) | 9780123978035 |
| DOIs | |
| State | Published - Oct 2013 |
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Keywords
- Chronic inflammatory diseases
- Immune-based therapy
- Immunopathogenesis
- Rheumatoid arthritis
ASJC Scopus subject areas
- Medicine(all)
- Dentistry(all)
Cite this
Rheumatoid Arthritis : Disease Pathophysiology. / Saxena, Ankit; Raychaudhuri, S. K.; Raychaudhuri, Siba P.
Inflammation, Advancing Age and Nutrition: Research and Clinical Interventions. Elsevier Inc., 2013. p. 215-229.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Rheumatoid Arthritis
T2 - Disease Pathophysiology
AU - Saxena, Ankit
AU - Raychaudhuri, S. K.
AU - Raychaudhuri, Siba P
PY - 2013/10
Y1 - 2013/10
N2 - Rheumatoid arthritis (RA) is a potentially destructive disease with profound impact on patients' function and quality of life. Newer therapeutic agents have revolutionized outcomes but have not resulted in best outcomes for all patients. However, RA is a heterogeneous disease comprising several subsets of patients with variations in pathogenesis. Elucidation of these differences and its molecular mechanisms may lead to better therapeutic approaches. To treat patients with RA more effectively, it is essential to intervene in the earliest events of the pathophysiologic processes of this disease. In this chapter, we will present the latest advances in the understanding of the disease process of RA and its clinical relevance.
AB - Rheumatoid arthritis (RA) is a potentially destructive disease with profound impact on patients' function and quality of life. Newer therapeutic agents have revolutionized outcomes but have not resulted in best outcomes for all patients. However, RA is a heterogeneous disease comprising several subsets of patients with variations in pathogenesis. Elucidation of these differences and its molecular mechanisms may lead to better therapeutic approaches. To treat patients with RA more effectively, it is essential to intervene in the earliest events of the pathophysiologic processes of this disease. In this chapter, we will present the latest advances in the understanding of the disease process of RA and its clinical relevance.
KW - Chronic inflammatory diseases
KW - Immune-based therapy
KW - Immunopathogenesis
KW - Rheumatoid arthritis
UR - http://www.scopus.com/inward/record.url?scp=84902395759&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84902395759&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-397803-5.00018-6
DO - 10.1016/B978-0-12-397803-5.00018-6
M3 - Chapter
AN - SCOPUS:84902395759
SN - 9780123978035
SP - 215
EP - 229
BT - Inflammation, Advancing Age and Nutrition: Research and Clinical Interventions
PB - Elsevier Inc.
ER -