Rheumatoid Arthritis: Disease Pathophysiology

Ankit Saxena, S. K. Raychaudhuri, Siba P Raychaudhuri

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Rheumatoid arthritis (RA) is a potentially destructive disease with profound impact on patients' function and quality of life. Newer therapeutic agents have revolutionized outcomes but have not resulted in best outcomes for all patients. However, RA is a heterogeneous disease comprising several subsets of patients with variations in pathogenesis. Elucidation of these differences and its molecular mechanisms may lead to better therapeutic approaches. To treat patients with RA more effectively, it is essential to intervene in the earliest events of the pathophysiologic processes of this disease. In this chapter, we will present the latest advances in the understanding of the disease process of RA and its clinical relevance.

Original languageEnglish (US)
Title of host publicationInflammation, Advancing Age and Nutrition: Research and Clinical Interventions
PublisherElsevier Inc.
Number of pages15
ISBN (Print)9780123978035
StatePublished - Oct 2013


  • Chronic inflammatory diseases
  • Immune-based therapy
  • Immunopathogenesis
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Medicine(all)
  • Dentistry(all)


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