Rheumatoid Arthritis: Disease Pathophysiology

Ankit Saxena; S. K. Raychaudhuri; Siba P Raychaudhuri

doi:10.1016/B978-0-12-397803-5.00018-6

Rheumatoid Arthritis: Disease Pathophysiology

Ankit Saxena, S. K. Raychaudhuri, Siba P Raychaudhuri

Rheumatology, Allergy, and Clinical Immunology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Rheumatoid arthritis (RA) is a potentially destructive disease with profound impact on patients' function and quality of life. Newer therapeutic agents have revolutionized outcomes but have not resulted in best outcomes for all patients. However, RA is a heterogeneous disease comprising several subsets of patients with variations in pathogenesis. Elucidation of these differences and its molecular mechanisms may lead to better therapeutic approaches. To treat patients with RA more effectively, it is essential to intervene in the earliest events of the pathophysiologic processes of this disease. In this chapter, we will present the latest advances in the understanding of the disease process of RA and its clinical relevance.

Original language	English (US)
Title of host publication	Inflammation, Advancing Age and Nutrition: Research and Clinical Interventions
Publisher	Elsevier Inc.
Pages	215-229
Number of pages	15
ISBN (Print)	9780123978035
DOIs	https://doi.org/10.1016/B978-0-12-397803-5.00018-6
State	Published - Oct 2013

Keywords

Chronic inflammatory diseases
Immune-based therapy
Immunopathogenesis
Rheumatoid arthritis

ASJC Scopus subject areas

Medicine(all)
Dentistry(all)

Access to Document

10.1016/B978-0-12-397803-5.00018-6

Fingerprint Dive into the research topics of 'Rheumatoid Arthritis: Disease Pathophysiology'. Together they form a unique fingerprint.

Cite this

Saxena, A., Raychaudhuri, S. K., & Raychaudhuri, S. P. (2013). Rheumatoid Arthritis: Disease Pathophysiology. In Inflammation, Advancing Age and Nutrition: Research and Clinical Interventions (pp. 215-229). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-397803-5.00018-6

@inbook{6d5785f95d3441ac894fb91a52ac22a2,

title = "Rheumatoid Arthritis: Disease Pathophysiology",

abstract = "Rheumatoid arthritis (RA) is a potentially destructive disease with profound impact on patients' function and quality of life. Newer therapeutic agents have revolutionized outcomes but have not resulted in best outcomes for all patients. However, RA is a heterogeneous disease comprising several subsets of patients with variations in pathogenesis. Elucidation of these differences and its molecular mechanisms may lead to better therapeutic approaches. To treat patients with RA more effectively, it is essential to intervene in the earliest events of the pathophysiologic processes of this disease. In this chapter, we will present the latest advances in the understanding of the disease process of RA and its clinical relevance.",

keywords = "Chronic inflammatory diseases, Immune-based therapy, Immunopathogenesis, Rheumatoid arthritis",

author = "Ankit Saxena and Raychaudhuri, {S. K.} and Raychaudhuri, {Siba P}",

year = "2013",

month = oct,

doi = "10.1016/B978-0-12-397803-5.00018-6",

language = "English (US)",

isbn = "9780123978035",

pages = "215--229",

booktitle = "Inflammation, Advancing Age and Nutrition: Research and Clinical Interventions",

publisher = "Elsevier Inc.",

}

TY - CHAP

T1 - Rheumatoid Arthritis

T2 - Disease Pathophysiology

AU - Saxena, Ankit

AU - Raychaudhuri, S. K.

AU - Raychaudhuri, Siba P

PY - 2013/10

Y1 - 2013/10

N2 - Rheumatoid arthritis (RA) is a potentially destructive disease with profound impact on patients' function and quality of life. Newer therapeutic agents have revolutionized outcomes but have not resulted in best outcomes for all patients. However, RA is a heterogeneous disease comprising several subsets of patients with variations in pathogenesis. Elucidation of these differences and its molecular mechanisms may lead to better therapeutic approaches. To treat patients with RA more effectively, it is essential to intervene in the earliest events of the pathophysiologic processes of this disease. In this chapter, we will present the latest advances in the understanding of the disease process of RA and its clinical relevance.

AB - Rheumatoid arthritis (RA) is a potentially destructive disease with profound impact on patients' function and quality of life. Newer therapeutic agents have revolutionized outcomes but have not resulted in best outcomes for all patients. However, RA is a heterogeneous disease comprising several subsets of patients with variations in pathogenesis. Elucidation of these differences and its molecular mechanisms may lead to better therapeutic approaches. To treat patients with RA more effectively, it is essential to intervene in the earliest events of the pathophysiologic processes of this disease. In this chapter, we will present the latest advances in the understanding of the disease process of RA and its clinical relevance.

KW - Chronic inflammatory diseases

KW - Immune-based therapy

KW - Immunopathogenesis

KW - Rheumatoid arthritis

UR - http://www.scopus.com/inward/record.url?scp=84902395759&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902395759&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-397803-5.00018-6

DO - 10.1016/B978-0-12-397803-5.00018-6

M3 - Chapter

AN - SCOPUS:84902395759

SN - 9780123978035

SP - 215

EP - 229

BT - Inflammation, Advancing Age and Nutrition: Research and Clinical Interventions

PB - Elsevier Inc.

ER -