Rhabdomyosarcoma in 8 horses

W. L. Castleman, D. E. Toplon, C. K. Clark, T. W. Heskett, L. L. Farina, T. M. Lynch, U. K. Bryant, F. Del Piero, Brian G Murphy, J. F. Edwards

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

This multi-institutional report describes 8 cases of rhabdomyosarcoma in horses. Four neoplasms were in the tongue and other areas of the mouth or head, 2 were in the abdominal wall, and 1 each was in right shoulder muscles and heart. Four rhabdomyosarcomas that were less than 10 cm in diameter were treated by surgical excision or radiation with no recurrence. Two neoplasms greater than 10 cm in diameter in the abdominal wall and the right shoulder were considered inoperable and led to decisions to euthanize the horses. Two neoplasms were incidental findings at necropsy. All the neoplasms were classified as embryonal except for 1 pleomorphic rhabdomyosarcoma. These 8 cases were evaluated with 9 published case reports of equine rhabdomyosarcoma. For all cases, the most common sites were limb muscles (5/17) and tongue (4/17). Metastasis was reported in 4 of the previously published cases; none was found in this study.

Original languageEnglish (US)
Pages (from-to)1144-1150
Number of pages7
JournalVeterinary Pathology
Volume48
Issue number6
DOIs
StatePublished - Nov 29 2011

Keywords

  • equine
  • horse
  • muscle
  • neoplasia
  • rhabdomyosarcoma

ASJC Scopus subject areas

  • veterinary(all)

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    Castleman, W. L., Toplon, D. E., Clark, C. K., Heskett, T. W., Farina, L. L., Lynch, T. M., Bryant, U. K., Del Piero, F., Murphy, B. G., & Edwards, J. F. (2011). Rhabdomyosarcoma in 8 horses. Veterinary Pathology, 48(6), 1144-1150. https://doi.org/10.1177/0300985810395785