Rhabdomyoblastic pulmonary lesions in a patient with Wilms tumor: Choristomas or metastases?

Theodore Zwerdling, Jonathan M Ducore, Douglas Taylor, Daniel C. West, Thomas Konia

Research output: Contribution to journalArticle

Abstract

New lesions that occur while patients are receiving treatment for malignant tumors may represent not only difficulties in arriving at the correct diagnosis, but also impact on subsequent therapeutic options. We encountered a patient developing new pulmonary lesions during and after receiving treatment for Stage II Wilms tumor (WT). The presence of mature rhabdomyoblasts in multiple biopsy specimens allowed rational decisions to be made regarding subsequent therapy. This and other published experiences suggest that patients with WT may develop choristomas or have tumors, which undergo cytodifferentiation. Methodologies are now available allowing differentiation of these two processes.

Original languageEnglish (US)
Pages (from-to)381-384
Number of pages4
JournalPediatric Blood and Cancer
Volume46
Issue number3
DOIs
StatePublished - Mar 2006

Keywords

  • Choristoma
  • Cytodifferentiation
  • Pulmonary lesions
  • Treatment
  • Wilms tumor

ASJC Scopus subject areas

  • Cancer Research
  • Pediatrics, Perinatology, and Child Health
  • Hematology

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