Review article

Nonsurgical treatment of non-acid reflux

J. Allen, S. P. Tinling, N. Johnston, Peter C Belafsky

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A significant percentage of people with gastro-oesophageal reflux disease (GERD) fail to improve with proton pump inhibitor (PPI) therapy. In this group of patients, refractory symptoms may be the result of non-acid reflux (NAR). Treatment of NAR ranges from simple reassurance to antireflux surgery. Current treatment algorithms include a combination of dietary and lifestyle modifications, antiacid medication, inhibition of transient lower oesophageal sphincter relaxations, and/or enhancement of the antireflux barrier. Because of the nonspecific nature of patient symptoms and the frequently elusive diagnosis, it is essential to exhaust conservative treatment options before resorting to surgical intervention. The purpose of this manuscript is to review the contemporary nonsurgical management of NAR.

Original languageEnglish (US)
Pages (from-to)66-70
Number of pages5
JournalAlimentary Pharmacology and Therapeutics
Volume33
Issue numberSUPPL. 1
DOIs
StatePublished - Apr 2011

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Esophageal Diseases
Diet Therapy
Lower Esophageal Sphincter
Proton Pump Inhibitors
Gastroesophageal Reflux
Life Style
Therapeutics
Conservative Treatment
Inhibition (Psychology)

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Review article : Nonsurgical treatment of non-acid reflux. / Allen, J.; Tinling, S. P.; Johnston, N.; Belafsky, Peter C.

In: Alimentary Pharmacology and Therapeutics, Vol. 33, No. SUPPL. 1, 04.2011, p. 66-70.

Research output: Contribution to journalArticle

Allen, J. ; Tinling, S. P. ; Johnston, N. ; Belafsky, Peter C. / Review article : Nonsurgical treatment of non-acid reflux. In: Alimentary Pharmacology and Therapeutics. 2011 ; Vol. 33, No. SUPPL. 1. pp. 66-70.
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