Reversible tubular lesion in pregnancy-induced hypertension detected by urinary β2-microglobulin

M. S. Krieger, J. Moodley, R. J. Norman, I. Jialal

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Serum and urine β2-microglobulin concentrations were measured in 17 primigravidas with mild pregnancy-induced hypertension and nine normotensive control patients matched for gestational age. Serum β2-microglobulin and creatinine clearance values were not different between the two groups but urinary excretion of β2-microglobulin was three times higher in the hypertensive patients. This difference disappeared within seven days of delivery. These results indicate that a reversible renal tubular lesion occurs in pregnancy-induced hypertension even in the absence of detectable proteinuria.

Original languageEnglish (US)
Pages (from-to)533-536
Number of pages4
JournalObstetrics and Gynecology
Volume63
Issue number4
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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    Krieger, M. S., Moodley, J., Norman, R. J., & Jialal, I. (1984). Reversible tubular lesion in pregnancy-induced hypertension detected by urinary β2-microglobulin. Obstetrics and Gynecology, 63(4), 533-536.