Abstract
Serum and urine β2-microglobulin concentrations were measured in 17 primigravidas with mild pregnancy-induced hypertension and nine normotensive control patients matched for gestational age. Serum β2-microglobulin and creatinine clearance values were not different between the two groups but urinary excretion of β2-microglobulin was three times higher in the hypertensive patients. This difference disappeared within seven days of delivery. These results indicate that a reversible renal tubular lesion occurs in pregnancy-induced hypertension even in the absence of detectable proteinuria.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 533-536 |
| Number of pages | 4 |
| Journal | Obstetrics and Gynecology |
| Volume | 63 |
| Issue number | 4 |
| State | Published - 1984 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Obstetrics and Gynecology
Cite this
Reversible tubular lesion in pregnancy-induced hypertension detected by urinary β2-microglobulin. / Krieger, M. S.; Moodley, J.; Norman, R. J.; Jialal, I.
In: Obstetrics and Gynecology, Vol. 63, No. 4, 1984, p. 533-536.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Reversible tubular lesion in pregnancy-induced hypertension detected by urinary β2-microglobulin
AU - Krieger, M. S.
AU - Moodley, J.
AU - Norman, R. J.
AU - Jialal, I.
PY - 1984
Y1 - 1984
N2 - Serum and urine β2-microglobulin concentrations were measured in 17 primigravidas with mild pregnancy-induced hypertension and nine normotensive control patients matched for gestational age. Serum β2-microglobulin and creatinine clearance values were not different between the two groups but urinary excretion of β2-microglobulin was three times higher in the hypertensive patients. This difference disappeared within seven days of delivery. These results indicate that a reversible renal tubular lesion occurs in pregnancy-induced hypertension even in the absence of detectable proteinuria.
AB - Serum and urine β2-microglobulin concentrations were measured in 17 primigravidas with mild pregnancy-induced hypertension and nine normotensive control patients matched for gestational age. Serum β2-microglobulin and creatinine clearance values were not different between the two groups but urinary excretion of β2-microglobulin was three times higher in the hypertensive patients. This difference disappeared within seven days of delivery. These results indicate that a reversible renal tubular lesion occurs in pregnancy-induced hypertension even in the absence of detectable proteinuria.
UR - http://www.scopus.com/inward/record.url?scp=0021332568&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021332568&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0021332568
VL - 63
SP - 533
EP - 536
JO - Obstetrics and Gynecology
JF - Obstetrics and Gynecology
SN - 0029-7844
IS - 4
ER -