Retraction notice: “Synthetic triterpenoids, CDDO-Imidazolide and CDDO-Ethyl amide, induce chondrogenesis” (Osteoarthritis and Cartilage (2012) 20(5) (446–450), (S1063458412000568), (10.1016/j.joca.2012.01.018))

N. Suh, S. Paul, H. J. Lee, T. Yoon, N. Shah, A. I. Son, A. H. Reddi, D. Medici, M. B. Sporn

Research output: Contribution to journalComment/debatepeer-review

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief due to serious problems with image manipulation. The Smad5 blots in Fig. 1(D) have been demonstrated to be identical with the β-actin blots from an antecedent publication in Biochemical Journal (Medici D, Potenta S, Kalluri R: Transforming growth factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signaling. Biochem J. 2011 Aug 1;437(3):515-20. doi: 10.1042/BJ20101500. PMID: 21585337). This has been the subject of a thorough investigation at the home institution of the author who produced the blots, and confirmed by the Editors of OAC. The co-authors of this study, Drs. Suh, Reddi, and Sporn have stated that all data for Table I were produced completely independently and they stand by the veracity of all but the offending Figure. The scientific community takes a very strong view on this matter and apologies are offered to readers of the journal that this was not detected previously.

Original languageEnglish (US)
Number of pages1
JournalOsteoarthritis and Cartilage
Volume28
Issue number6
DOIs
StatePublished - Jun 2020

ASJC Scopus subject areas

  • Rheumatology
  • Biomedical Engineering
  • Orthopedics and Sports Medicine

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