Retinal oscillations carry visual information to cortex

Kilian Koepsell, Xin Wang, Vishal Vaingankar, Yichun Wei, Qingbo Wang, Daniel L. Rathbun, William Martin Usrey, Judith A. Hirsch, Friedrich T. Sommer

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Thalamic relay cells fire action potentials that transmit information from retina to cortex. The amount of information that spike trains encode is usually estimated from the precision of spike timing with respect to the stimulus. Sensory input, however, is only one factor that influences neural activity. For example, intrinsic dynamics, such as oscillations of networks of neurons, also modulate firing pattern. Here, we asked if retinal oscillations might help to convey information to neurons downstream. Specifically, we made whole-cell recordings from relay cells to reveal retinal inputs (EPSPs) and thalamic outputs (spikes) and then analyzed these events with information theory. Our results show that thalamic spike trains operate as two multiplexed channels. One channel, which occupies a low frequency band (<30 Hz), is encoded by average firing rate with respect to the stimulus and carries information about local changes in the visual field over time. The other operates in the gamma frequency band (40-80 Hz) and is encoded by spike timing relative to retinal oscillations. At times, the second channel conveyed even more information than the first. Because retinal oscillations involve extensive networks of ganglion cells, it is likely that the second channel transmits information about global features of the visual scene.

Original languageEnglish (US)
Article number4
JournalFrontiers in Systems Neuroscience
Volume3
Issue numberAPR
DOIs
StatePublished - Apr 10 2009

Fingerprint

Information Theory
Neurons
Excitatory Postsynaptic Potentials
Patch-Clamp Techniques
Visual Fields
Ganglia
Action Potentials
Retina

Keywords

  • LGN
  • Natural stimuli
  • Oscillations
  • Retina
  • Visual coding

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Cellular and Molecular Neuroscience
  • Cognitive Neuroscience
  • Developmental Neuroscience

Cite this

Koepsell, K., Wang, X., Vaingankar, V., Wei, Y., Wang, Q., Rathbun, D. L., ... Sommer, F. T. (2009). Retinal oscillations carry visual information to cortex. Frontiers in Systems Neuroscience, 3(APR), [4]. https://doi.org/10.3389/neuro.06.004.2009

Retinal oscillations carry visual information to cortex. / Koepsell, Kilian; Wang, Xin; Vaingankar, Vishal; Wei, Yichun; Wang, Qingbo; Rathbun, Daniel L.; Usrey, William Martin; Hirsch, Judith A.; Sommer, Friedrich T.

In: Frontiers in Systems Neuroscience, Vol. 3, No. APR, 4, 10.04.2009.

Research output: Contribution to journalArticle

Koepsell, K, Wang, X, Vaingankar, V, Wei, Y, Wang, Q, Rathbun, DL, Usrey, WM, Hirsch, JA & Sommer, FT 2009, 'Retinal oscillations carry visual information to cortex', Frontiers in Systems Neuroscience, vol. 3, no. APR, 4. https://doi.org/10.3389/neuro.06.004.2009
Koepsell K, Wang X, Vaingankar V, Wei Y, Wang Q, Rathbun DL et al. Retinal oscillations carry visual information to cortex. Frontiers in Systems Neuroscience. 2009 Apr 10;3(APR). 4. https://doi.org/10.3389/neuro.06.004.2009
Koepsell, Kilian ; Wang, Xin ; Vaingankar, Vishal ; Wei, Yichun ; Wang, Qingbo ; Rathbun, Daniel L. ; Usrey, William Martin ; Hirsch, Judith A. ; Sommer, Friedrich T. / Retinal oscillations carry visual information to cortex. In: Frontiers in Systems Neuroscience. 2009 ; Vol. 3, No. APR.
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