Results of surgical excision and evaluation of factors associated with survival time in dogs with lingual neoplasia: 97 cases (1995-2008)

William T Culp, Nicole Ehrhart, Stephen J. Withrow, Robert B Rebhun, Sarah Boston, Paolo Buracco, Alexander M. Reiter, Sandra P. Schallberger, Charles F. Aldridge, Michael S Kent, Philipp Mayhew, Dorothy C. Brown

Research output: Contribution to journalArticle

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Abstract

Objective-To describe the clinical characteristics, treatments, outcomes, and factors as-sociated with survival time in a cohort of dogs with lingual neoplasia that underwent surgi-cal excision. Design-Retrospective case series.Animals-97 client-owned dogs.Procedures-Medical records of dogs with a lingual tumor examined between 1995 and 2008 were reviewed. Records were included if a lingual tumor was confirmed by histologic examination and surgical excision of the mass was attempted. Data were recorded and analyzed to identify prognostic factors. Results-Clinical signs were mostly related to the oral cavity. For 93 dogs, marginal exci-sion, subtotal glossectomy, and near-total glossectomy were performed in 35 (38%), 55 (59%), and 3 (3%), respectively. Surgery-related complications were rare, but 27 (28%) dogs had tumor recurrence. The most common histopathologic diagnoses for the 97 dogs were squamous cell carcinoma (31 [32%]) and malignant melanoma (29 [30%]). Eighteen (19%) dogs developed metastatic disease, and the overall median survival time was 483 days. Median survival time was 216 days for dogs with squamous cell carcinoma and 241 days for dogs with malignant melanoma. Dogs with lingual tumors ≥ 2 cm in diameter at diagnosis had a significantly shorter survival time than did dogs with tumors < 2 cm. Conclusions and Clinical Relevance-Similar to previous studies, results indicated that lingual tumors are most commonly malignant, and squamous cell carcinoma and malignant melanoma predominate. A thorough physical examination to identify lingual tumors at an early stage and surgical treatment after tumor identification are recommended because tumor size significantly affected survival time.

Original languageEnglish (US)
Pages (from-to)1392-1397
Number of pages6
JournalJournal of the American Veterinary Medical Association
Volume242
Issue number10
DOIs
StatePublished - May 2013

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excision
tongue
Tongue
Dogs
neoplasms
dogs
Neoplasms
squamous cell carcinoma
melanoma
Glossectomy
Squamous Cell Carcinoma
Melanoma
clinical examination
Physical Examination
Medical Records
Mouth
mouth
surgery

ASJC Scopus subject areas

  • veterinary(all)

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Results of surgical excision and evaluation of factors associated with survival time in dogs with lingual neoplasia : 97 cases (1995-2008). / Culp, William T; Ehrhart, Nicole; Withrow, Stephen J.; Rebhun, Robert B; Boston, Sarah; Buracco, Paolo; Reiter, Alexander M.; Schallberger, Sandra P.; Aldridge, Charles F.; Kent, Michael S; Mayhew, Philipp; Brown, Dorothy C.

In: Journal of the American Veterinary Medical Association, Vol. 242, No. 10, 05.2013, p. 1392-1397.

Research output: Contribution to journalArticle

Culp, William T ; Ehrhart, Nicole ; Withrow, Stephen J. ; Rebhun, Robert B ; Boston, Sarah ; Buracco, Paolo ; Reiter, Alexander M. ; Schallberger, Sandra P. ; Aldridge, Charles F. ; Kent, Michael S ; Mayhew, Philipp ; Brown, Dorothy C. / Results of surgical excision and evaluation of factors associated with survival time in dogs with lingual neoplasia : 97 cases (1995-2008). In: Journal of the American Veterinary Medical Association. 2013 ; Vol. 242, No. 10. pp. 1392-1397.
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abstract = "Objective-To describe the clinical characteristics, treatments, outcomes, and factors as-sociated with survival time in a cohort of dogs with lingual neoplasia that underwent surgi-cal excision. Design-Retrospective case series.Animals-97 client-owned dogs.Procedures-Medical records of dogs with a lingual tumor examined between 1995 and 2008 were reviewed. Records were included if a lingual tumor was confirmed by histologic examination and surgical excision of the mass was attempted. Data were recorded and analyzed to identify prognostic factors. Results-Clinical signs were mostly related to the oral cavity. For 93 dogs, marginal exci-sion, subtotal glossectomy, and near-total glossectomy were performed in 35 (38{\%}), 55 (59{\%}), and 3 (3{\%}), respectively. Surgery-related complications were rare, but 27 (28{\%}) dogs had tumor recurrence. The most common histopathologic diagnoses for the 97 dogs were squamous cell carcinoma (31 [32{\%}]) and malignant melanoma (29 [30{\%}]). Eighteen (19{\%}) dogs developed metastatic disease, and the overall median survival time was 483 days. Median survival time was 216 days for dogs with squamous cell carcinoma and 241 days for dogs with malignant melanoma. Dogs with lingual tumors ≥ 2 cm in diameter at diagnosis had a significantly shorter survival time than did dogs with tumors < 2 cm. Conclusions and Clinical Relevance-Similar to previous studies, results indicated that lingual tumors are most commonly malignant, and squamous cell carcinoma and malignant melanoma predominate. A thorough physical examination to identify lingual tumors at an early stage and surgical treatment after tumor identification are recommended because tumor size significantly affected survival time.",
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AU - Ehrhart, Nicole

AU - Withrow, Stephen J.

AU - Rebhun, Robert B

AU - Boston, Sarah

AU - Buracco, Paolo

AU - Reiter, Alexander M.

AU - Schallberger, Sandra P.

AU - Aldridge, Charles F.

AU - Kent, Michael S

AU - Mayhew, Philipp

AU - Brown, Dorothy C.

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