Abstract
Solitary horizontal cells dissociated from goldfish retinas depolarized when exposed to micromolar doses of either l-glutamate or kainic acid. The responses to both of these agonists were antagonized by d-aspartate, and unaffected by l-aspartate, l-glutamic acid diethyl ester and folic acid. The results of the present study thus suggest that l-glutamate and kainic acid may produce depolarizations of horizontal cells by interacting with pharmacologically similar membrane receptors.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 25-32 |
| Number of pages | 8 |
| Journal | Brain Research |
| Volume | 298 |
| Issue number | 1 |
| DOIs | |
| State | Published - Apr 23 1984 |
| Externally published | Yes |
Keywords
- d-aspartate
- horizontal cell
- kainic acid
- l-glutamate
- l-glutamate antagonists
- retina
ASJC Scopus subject areas
- Developmental Biology
- Molecular Biology
- Clinical Neurology
- Neuroscience(all)