Responses of solitary retinal horizontal cells to l-glutamate and kainic acid are antagonized by d-aspartate

Andrew Ishida

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Solitary horizontal cells dissociated from goldfish retinas depolarized when exposed to micromolar doses of either l-glutamate or kainic acid. The responses to both of these agonists were antagonized by d-aspartate, and unaffected by l-aspartate, l-glutamic acid diethyl ester and folic acid. The results of the present study thus suggest that l-glutamate and kainic acid may produce depolarizations of horizontal cells by interacting with pharmacologically similar membrane receptors.

Original languageEnglish (US)
Pages (from-to)25-32
Number of pages8
JournalBrain Research
Volume298
Issue number1
DOIs
StatePublished - Apr 23 1984
Externally publishedYes

Keywords

  • d-aspartate
  • horizontal cell
  • kainic acid
  • l-glutamate
  • l-glutamate antagonists
  • retina

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

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