Response to comment on "Modafinil shifts human locus coeruleus to low-tonic, high-phasic activity during functional MRI"

Michael J. Minzenberg; Andrew J. Watrous; Jong H. Yoon; Christian La; Stefan Ursu; Cameron S Carter

doi:10.1126/science.1177948

Response to comment on "Modafinil shifts human locus coeruleus to low-tonic, high-phasic activity during functional MRI"

Michael J. Minzenberg, Andrew J. Watrous, Jong H. Yoon, Christian La, Stefan Ursu, Cameron S Carter

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Contrary to the arguments put forth by Astafiev et at., our new analyses and high-resolution replication show that modulation of brain activity by the cognitive enhancing drug modafinil indeed localizes to the locus coeruleus. The authors' critical stance regarding blood oxygen level-dependent imaging in the brainstem does not follow from their data.

Original language	English (US)
Journal	Science
Volume	328
Issue number	5976
DOIs	https://doi.org/10.1126/science.1177948
State	Published - Apr 16 2010

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AU - Yoon, Jong H.

AU - La, Christian

AU - Ursu, Stefan

AU - Carter, Cameron S

PY - 2010/4/16

Y1 - 2010/4/16

N2 - Contrary to the arguments put forth by Astafiev et at., our new analyses and high-resolution replication show that modulation of brain activity by the cognitive enhancing drug modafinil indeed localizes to the locus coeruleus. The authors' critical stance regarding blood oxygen level-dependent imaging in the brainstem does not follow from their data.

AB - Contrary to the arguments put forth by Astafiev et at., our new analyses and high-resolution replication show that modulation of brain activity by the cognitive enhancing drug modafinil indeed localizes to the locus coeruleus. The authors' critical stance regarding blood oxygen level-dependent imaging in the brainstem does not follow from their data.

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Response to comment on "Modafinil shifts human locus coeruleus to low-tonic, high-phasic activity during functional MRI"

Abstract

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