Response to alternative antidepressants in imipramine nonresponders with bulimia nervosa

J. E. Mitchell, R. L. Pyle, E. D. Eckert, D. Hatsukami, Claire Pomeroy, R. Zimmerman

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

The authors report the results of open-label antidepressant trials in a series of normal weight bulimic women who showed an inadequate response to an initial trial of imipramine hydrochloride as part of a treatment comparison study. The results indicate that a significant percentage of subjects responded to a second trial of an alternative agent. Overall, 47% had a complete remission of symptoms during the second trial, usually with a monoamine oxidase inhibitor or fluoxetine. The authors stress the importance of persisting in trials of alternative agents if bulimic patients fail to respond to an initial trial.

Original languageEnglish (US)
Pages (from-to)291-293
Number of pages3
JournalJournal of Clinical Psychopharmacology
Volume9
Issue number4
StatePublished - 1989
Externally publishedYes

Fingerprint

Bulimia Nervosa
Monoamine Oxidase Inhibitors
Imipramine
Fluoxetine
Proxy
Antidepressive Agents
Weights and Measures
Therapeutics

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Psychiatry and Mental health
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Mitchell, J. E., Pyle, R. L., Eckert, E. D., Hatsukami, D., Pomeroy, C., & Zimmerman, R. (1989). Response to alternative antidepressants in imipramine nonresponders with bulimia nervosa. Journal of Clinical Psychopharmacology, 9(4), 291-293.

Response to alternative antidepressants in imipramine nonresponders with bulimia nervosa. / Mitchell, J. E.; Pyle, R. L.; Eckert, E. D.; Hatsukami, D.; Pomeroy, Claire; Zimmerman, R.

In: Journal of Clinical Psychopharmacology, Vol. 9, No. 4, 1989, p. 291-293.

Research output: Contribution to journalArticle

Mitchell, JE, Pyle, RL, Eckert, ED, Hatsukami, D, Pomeroy, C & Zimmerman, R 1989, 'Response to alternative antidepressants in imipramine nonresponders with bulimia nervosa', Journal of Clinical Psychopharmacology, vol. 9, no. 4, pp. 291-293.
Mitchell JE, Pyle RL, Eckert ED, Hatsukami D, Pomeroy C, Zimmerman R. Response to alternative antidepressants in imipramine nonresponders with bulimia nervosa. Journal of Clinical Psychopharmacology. 1989;9(4):291-293.
Mitchell, J. E. ; Pyle, R. L. ; Eckert, E. D. ; Hatsukami, D. ; Pomeroy, Claire ; Zimmerman, R. / Response to alternative antidepressants in imipramine nonresponders with bulimia nervosa. In: Journal of Clinical Psychopharmacology. 1989 ; Vol. 9, No. 4. pp. 291-293.
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