Response of house finches to infection with sympatric and allopatric strains of western equine encephalomyelitis and St. Louis encephalitis viruses from California

William Reisen, Laura D. Kramer, Robert E. Chiles, Vincent M. Martinez, Bruce F. Eldridge

Research output: Contribution to journalArticle

15 Scopus citations


Adult house finches from Kern County were inoculated subcutaneously with recent sympatric and allopatric isolates of western equine encephalomyelitis and St. Louis encephalitis (SLE) viruses made from Culex tarsalis Coquillett collected in Kern County and Coachella Valley, CA, respectively. Virulence, as measured by the amplitude of the viremia response during days 1 and 2 postinfection, varied significantly among strains, but independently of geographic origin. The intensity of the immune response, as measured by an enzyme immunoassay and a plaque reduction neutralization test, seemed to be independent of virulence, especially for SLE where some strains failed to produce a detectable viremia but elicited a strong antibody response. Our preliminary data indicated that strain virulence may be associated with the level of enzootic activity during the year of isolation.

Original languageEnglish (US)
Pages (from-to)259-264
Number of pages6
JournalJournal of Medical Entomology
Issue number2
StatePublished - Jan 1 2000



  • Antibody
  • House finch
  • Infection
  • St. Louis encephalitis virus
  • Viremia
  • Western equine encephalomyelitis virus

ASJC Scopus subject areas

  • Parasitology
  • veterinary(all)
  • Insect Science
  • Infectious Diseases

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