Resources for genetic management and genomics research on non-human primates at the National Primate Research Centers (NPRCs)

S. Kanthaswamy, J. P. Capitanio, C. J. Dubay, B. Ferguson, T. Folks, J. C. Ha, C. E. Hotchkiss, Z. P. Johnson, M. G. Katze, L. S. Kean, H. Michael Kubisch, S. Lank, Leslie A Lyons, G. M. Miller, J. Nylander, D. H. O'Connor, R. E. Palermo, D. G. Smith, E. J. Vallender, R. W. WisemanJ. Rogers

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

The National Primate Research Centers (NPRCs) established Working Groups (WGs) for developing resources and mechanisms to facilitate collaborations among non-human primate (NHP) researchers. Here we report the progress of the Genome Banking and the Genetics and Genomics WGs in developing resources to advance the exchange, analysis and comparison of NHP genetic and genomic data across the NPRCs.The Genome Banking WG has established a National NHP DNA bank comprising 1250 DNA samples from unrelated animals and family trios from the 10 NHP species housed within the NPRC system. The Genetics and Genomics WG is developing SNP arrays that will provide a uniform, highly informative, efficient and low-cost method for rhesus and long-tailed macaque genotyping across the eight NPRCs. This WG is also establishing a Biomedical Informatics Research Network-based portal for shared bioinformatics resources including vital statistics, genotype and population data and information on the National NHP DNA bank.

Original languageEnglish (US)
Pages (from-to)17-23
Number of pages7
JournalJournal of Medical Primatology
Volume38
Issue numberSUPPL. 1
DOIs
StatePublished - Oct 2009

Keywords

  • Ancestry estimation
  • Biomedical information research network
  • Databases
  • DNA bank
  • Genotype data
  • Information systems
  • Parentage testing
  • Population genetics
  • Single nucleotide polymorphisms
  • Web portal

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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    Kanthaswamy, S., Capitanio, J. P., Dubay, C. J., Ferguson, B., Folks, T., Ha, J. C., Hotchkiss, C. E., Johnson, Z. P., Katze, M. G., Kean, L. S., Michael Kubisch, H., Lank, S., Lyons, L. A., Miller, G. M., Nylander, J., O'Connor, D. H., Palermo, R. E., Smith, D. G., Vallender, E. J., ... Rogers, J. (2009). Resources for genetic management and genomics research on non-human primates at the National Primate Research Centers (NPRCs). Journal of Medical Primatology, 38(SUPPL. 1), 17-23. https://doi.org/10.1111/j.1600-0684.2009.00371.x