Resident dendritic cells in the epidermis: Langerhans cells, Merkel cells and melanocytes

Stephen D White, Julie A. Yager

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

In addition to the keratinocytes, the epidermis contains resident cells of dendritic morphology. These are principally the Langerhans cell, Merkel cell and melanocyte. These cells have a number of different funtions in the integument. The melanocyte is responsible for skin pigmentation, and protection against UV radiation, and may also play a role in the modulation of cutaneous inflammation. The Langerhans cell aids in the immunological monitoring of the body's external surfaces. The Merkel cell has neuroendocrine functions. This review gives an overview of the structure and function of these three important cells of the skin.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalVeterinary Dermatology
Volume6
Issue number1
StatePublished - 1995
Externally publishedYes

Fingerprint

Merkel Cells
Langerhans cells
Langerhans Cells
melanocytes
Melanocytes
epidermis (animal)
dendritic cells
Epidermis
Dendritic Cells
Skin Pigmentation
Immunologic Monitoring
Skin
Keratinocytes
skin (animal)
cells
Radiation
Inflammation
keratinocytes
integument
pigmentation

Keywords

  • Dendritic cells
  • Epidermis
  • Langerhans cell
  • Melanocyte
  • Merkel cell
  • Veterinary dermatology

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Resident dendritic cells in the epidermis : Langerhans cells, Merkel cells and melanocytes. / White, Stephen D; Yager, Julie A.

In: Veterinary Dermatology, Vol. 6, No. 1, 1995, p. 1-8.

Research output: Contribution to journalArticle

@article{3e5cee4a32d849fca0fadf21f4699767,
title = "Resident dendritic cells in the epidermis: Langerhans cells, Merkel cells and melanocytes",
abstract = "In addition to the keratinocytes, the epidermis contains resident cells of dendritic morphology. These are principally the Langerhans cell, Merkel cell and melanocyte. These cells have a number of different funtions in the integument. The melanocyte is responsible for skin pigmentation, and protection against UV radiation, and may also play a role in the modulation of cutaneous inflammation. The Langerhans cell aids in the immunological monitoring of the body's external surfaces. The Merkel cell has neuroendocrine functions. This review gives an overview of the structure and function of these three important cells of the skin.",
keywords = "Dendritic cells, Epidermis, Langerhans cell, Melanocyte, Merkel cell, Veterinary dermatology",
author = "White, {Stephen D} and Yager, {Julie A.}",
year = "1995",
language = "English (US)",
volume = "6",
pages = "1--8",
journal = "Veterinary Dermatology",
issn = "0959-4493",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Resident dendritic cells in the epidermis

T2 - Langerhans cells, Merkel cells and melanocytes

AU - White, Stephen D

AU - Yager, Julie A.

PY - 1995

Y1 - 1995

N2 - In addition to the keratinocytes, the epidermis contains resident cells of dendritic morphology. These are principally the Langerhans cell, Merkel cell and melanocyte. These cells have a number of different funtions in the integument. The melanocyte is responsible for skin pigmentation, and protection against UV radiation, and may also play a role in the modulation of cutaneous inflammation. The Langerhans cell aids in the immunological monitoring of the body's external surfaces. The Merkel cell has neuroendocrine functions. This review gives an overview of the structure and function of these three important cells of the skin.

AB - In addition to the keratinocytes, the epidermis contains resident cells of dendritic morphology. These are principally the Langerhans cell, Merkel cell and melanocyte. These cells have a number of different funtions in the integument. The melanocyte is responsible for skin pigmentation, and protection against UV radiation, and may also play a role in the modulation of cutaneous inflammation. The Langerhans cell aids in the immunological monitoring of the body's external surfaces. The Merkel cell has neuroendocrine functions. This review gives an overview of the structure and function of these three important cells of the skin.

KW - Dendritic cells

KW - Epidermis

KW - Langerhans cell

KW - Melanocyte

KW - Merkel cell

KW - Veterinary dermatology

UR - http://www.scopus.com/inward/record.url?scp=21844487158&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=21844487158&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:21844487158

VL - 6

SP - 1

EP - 8

JO - Veterinary Dermatology

JF - Veterinary Dermatology

SN - 0959-4493

IS - 1

ER -