TY - JOUR
T1 - Reproducibility of macular thickness measurement among five OCT instruments
T2 - Effects of image resolution, image registration, and eye tracking
AU - Chin, Eric K.
AU - Sedeek, Ragui W.
AU - Li, Yueju
AU - Beckett, Laurel A
AU - Redenbo, Ellen
AU - Chandra, Karishma
AU - Park, Susanna Soon Chun
PY - 2012/3
Y1 - 2012/3
N2 - ■ BACKGROUND AND OBJECTIVE: To study the effect of image resolution, eye tracking, and image registration on central macular thickness reproducibility (rCMT) among spectral-domain and time-domain optical coherence tomography (SD-OCT and TD-OCT) instruments. ■ PATIENTS AND METHODS: Seventy-six eyes were imaged (44 normal, 32 maculopathy) either twice using four SD-OCT and one TD-OCT devices or three times using Spectralis SD-OCT (with and without eye tracking) (Heidelberg Engineering, Inc., Heidelberg, Germany). Cirrus images (Carl Zeiss Meditec, Dublin, CA) were further analyzed with three-point image registration. ■ RESULTS: All instruments had superior rCMT in normal versus pathologic eyes (P < .001). No difference in rCMT was noted among instruments in normal eyes (P = .92), but TD-OCT was superior to SD-OCT (P = .017) in pathologic eyes. Cirrus image registration improved rCMT for normal eyes (P = .04), with borderline improvement in pathologic eyes (P = .06). Spectralis eye tracking improved rCMT in normal (P = .01) and pathologic (P = .004) eyes. ■ CONCLUSION: Higher image resolution with SD-OCT may not improve rCMT, but image registration and eye tracking options may improve rCMT.
AB - ■ BACKGROUND AND OBJECTIVE: To study the effect of image resolution, eye tracking, and image registration on central macular thickness reproducibility (rCMT) among spectral-domain and time-domain optical coherence tomography (SD-OCT and TD-OCT) instruments. ■ PATIENTS AND METHODS: Seventy-six eyes were imaged (44 normal, 32 maculopathy) either twice using four SD-OCT and one TD-OCT devices or three times using Spectralis SD-OCT (with and without eye tracking) (Heidelberg Engineering, Inc., Heidelberg, Germany). Cirrus images (Carl Zeiss Meditec, Dublin, CA) were further analyzed with three-point image registration. ■ RESULTS: All instruments had superior rCMT in normal versus pathologic eyes (P < .001). No difference in rCMT was noted among instruments in normal eyes (P = .92), but TD-OCT was superior to SD-OCT (P = .017) in pathologic eyes. Cirrus image registration improved rCMT for normal eyes (P = .04), with borderline improvement in pathologic eyes (P = .06). Spectralis eye tracking improved rCMT in normal (P = .01) and pathologic (P = .004) eyes. ■ CONCLUSION: Higher image resolution with SD-OCT may not improve rCMT, but image registration and eye tracking options may improve rCMT.
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U2 - 10.3928/15428877-20111222-02
DO - 10.3928/15428877-20111222-02
M3 - Article
C2 - 22201525
AN - SCOPUS:84859834440
VL - 43
SP - 97
EP - 108
JO - Ophthalmic Surgery
JF - Ophthalmic Surgery
SN - 2325-8160
IS - 2
ER -