Report of a Hürthle cell neoplasm in a peripubertal girl

Andrew A. Bremer; Brian J. Feldman; Gioia Iezza; Orlo H. Clark; Stephen M. Rosenthal

doi:10.1089/thy.2006.0214

Report of a Hürthle cell neoplasm in a peripubertal girl

Andrew A. Bremer, Brian J. Feldman, Gioia Iezza, Orlo H. Clark, Stephen M. Rosenthal

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Abstract

Thyroid nodules are rare in children compared to adults. Although most thyroid nodules are benign, the risk of malignancy is greater in pediatric patients. Papillary and follicular cell tumors account for the majority of thyroid neoplasms; Hürthle cell tumors account for less than 5%. Despite being uncommon, malignant Hurthle cell tumors are potentially more aggressive than papillary and follicular cell tumors. Therefore, distinguishing between types of thyroid neoplasms in a timely fashion has implications for prognosis and therapy. We describe a 12-year-old peripubertal girl who presented with a large right-sided thyroid nodule that was subsequently diagnosed as a Hürthle cell adenoma. To our knowledge, she represents the youngest patient with a Hürthle cell neoplasm.

Original language	English (US)
Pages (from-to)	175-178
Number of pages	4
Journal	Thyroid
Volume	17
Issue number	2
DOIs	https://doi.org/10.1089/thy.2006.0214
State	Published - Feb 2007

ASJC Scopus subject areas

Endocrinology

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10.1089/thy.2006.0214

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title = "Report of a H{\"u}rthle cell neoplasm in a peripubertal girl",

abstract = "Thyroid nodules are rare in children compared to adults. Although most thyroid nodules are benign, the risk of malignancy is greater in pediatric patients. Papillary and follicular cell tumors account for the majority of thyroid neoplasms; H{\"u}rthle cell tumors account for less than 5%. Despite being uncommon, malignant Hurthle cell tumors are potentially more aggressive than papillary and follicular cell tumors. Therefore, distinguishing between types of thyroid neoplasms in a timely fashion has implications for prognosis and therapy. We describe a 12-year-old peripubertal girl who presented with a large right-sided thyroid nodule that was subsequently diagnosed as a H{\"u}rthle cell adenoma. To our knowledge, she represents the youngest patient with a H{\"u}rthle cell neoplasm.",

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AU - Feldman, Brian J.

AU - Iezza, Gioia

AU - Clark, Orlo H.

AU - Rosenthal, Stephen M.

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N2 - Thyroid nodules are rare in children compared to adults. Although most thyroid nodules are benign, the risk of malignancy is greater in pediatric patients. Papillary and follicular cell tumors account for the majority of thyroid neoplasms; Hürthle cell tumors account for less than 5%. Despite being uncommon, malignant Hurthle cell tumors are potentially more aggressive than papillary and follicular cell tumors. Therefore, distinguishing between types of thyroid neoplasms in a timely fashion has implications for prognosis and therapy. We describe a 12-year-old peripubertal girl who presented with a large right-sided thyroid nodule that was subsequently diagnosed as a Hürthle cell adenoma. To our knowledge, she represents the youngest patient with a Hürthle cell neoplasm.

AB - Thyroid nodules are rare in children compared to adults. Although most thyroid nodules are benign, the risk of malignancy is greater in pediatric patients. Papillary and follicular cell tumors account for the majority of thyroid neoplasms; Hürthle cell tumors account for less than 5%. Despite being uncommon, malignant Hurthle cell tumors are potentially more aggressive than papillary and follicular cell tumors. Therefore, distinguishing between types of thyroid neoplasms in a timely fashion has implications for prognosis and therapy. We describe a 12-year-old peripubertal girl who presented with a large right-sided thyroid nodule that was subsequently diagnosed as a Hürthle cell adenoma. To our knowledge, she represents the youngest patient with a Hürthle cell neoplasm.

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Report of a Hürthle cell neoplasm in a peripubertal girl

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