Repeated dosing of botulinum toxin type A for upper limb spasticity following stroke

Mark Forrest Gordon, A. Brashear, E. Elovic, D. Kassicieh, C. Marciniak, J. Liu, C. Turkel

Research output: Contribution to journalArticle

71 Scopus citations

Abstract

The authors evaluated the long-term efficacy and safety of botulinum toxin type A (BTX-A) in poststroke spasticity patients who completed a 12-week placebo-controlled study and received multiple open-label treatments with 200 to 240 U BTX-A for 42 weeks. Significant and sustained improvements were observed for Disability Assessment and Ashworth scores. Adverse events were generally mild. This extension of a double-blind study demonstrates that repeated treatments of BTX-A significantly improve function and tone in spasticity.

Original languageEnglish (US)
Pages (from-to)1971-1973
Number of pages3
JournalNeurology
Volume63
Issue number10
DOIs
StatePublished - Nov 23 2004
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'Repeated dosing of botulinum toxin type A for upper limb spasticity following stroke'. Together they form a unique fingerprint.

  • Cite this

    Gordon, M. F., Brashear, A., Elovic, E., Kassicieh, D., Marciniak, C., Liu, J., & Turkel, C. (2004). Repeated dosing of botulinum toxin type A for upper limb spasticity following stroke. Neurology, 63(10), 1971-1973. https://doi.org/10.1212/01.WNL.0000144349.95487.91