Reorganization and expansion of the nidoviral family Arteriviridae

Jens H. Kuhn, Michael Lauck, Adam L. Bailey, Alexey M. Shchetinin, Tatyana V. Vishnevskaya, Yīmíng Bào, Terry Fei Fan Ng, Matthew LeBreton, Bradley S. Schneider, Amethyst Gillis, Ubald Tamoufe, Joseph Le Doux Diffo, Jean Michel Takuo, Nikola O. Kondov, Lark L Schneider, Nathan D. Wolfe, Eric Delwart, Anna N. Clawson, Elena Postnikova, Laura BollingerMatthew G. Lackemeyer, Sheli R. Radoshitzky, Gustavo Palacios, Jiro Wada, Zinaida V. Shevtsova, Peter B. Jahrling, Boris A. Lapin, Petr G. Deriabin, Magdalena Dunowska, Sergey V. Alkhovsky, Jeffrey Rogers, Thomas C. Friedrich, David H. O’Connor, Tony L. Goldberg

Research output: Contribution to journalArticle

95 Scopus citations

Abstract

The family Arteriviridae presently includes a single genus Arterivirus. This genus includes four species as the taxonomic homes for equine arteritis virus (EAV), lactate dehydrogenase-elevating virus (LDV), porcine respiratory and reproductive syndrome virus (PRRSV), and simian hemorrhagic fever virus (SHFV), respectively. A revision of this classification is urgently needed to accommodate the recent description of eleven highly divergent simian arteriviruses in diverse African nonhuman primates, one novel arterivirus in an African forest giant pouched rat, and a novel arterivirus in common brushtails in New Zealand. In addition, the current arterivirus nomenclature is not in accordance with the most recent version of the International Code of Virus Classification and Nomenclature. Here we outline an updated, amended, and improved arterivirus taxonomy based on current data. Taxon-specific sequence cut-offs are established relying on a newly established open reading frame 1b phylogeny and pairwise sequence comparison (PASC) of coding-complete arterivirus genomes. As a result, the current genus Arterivirus is replaced by five genera: Equartevirus (for EAV), Rodartevirus (LDV + PRRSV), Simartevirus (SHFV + simian arteriviruses), Nesartevirus (for the arterivirus from forest giant pouched rats), and Dipartevirus (common brushtail arterivirus). The current species Porcine reproductive and respiratory syndrome virus is divided into two species to accommodate the clear divergence of the European and American “types” of PRRSV, both of which now receive virus status. The current species Simian hemorrhagic fever virus is divided into nine species to accommodate the twelve known simian arteriviruses. Non-Latinized binomial species names are introduced to replace all current species names to clearly differentiate them from virus names, which remain largely unchanged.

Original languageEnglish (US)
Pages (from-to)755-768
Number of pages14
JournalArchives of Virology
Volume161
Issue number3
DOIs
StatePublished - Mar 1 2016

ASJC Scopus subject areas

  • Virology

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    Kuhn, J. H., Lauck, M., Bailey, A. L., Shchetinin, A. M., Vishnevskaya, T. V., Bào, Y., Ng, T. F. F., LeBreton, M., Schneider, B. S., Gillis, A., Tamoufe, U., Diffo, J. L. D., Takuo, J. M., Kondov, N. O., Schneider, L. L., Wolfe, N. D., Delwart, E., Clawson, A. N., Postnikova, E., ... Goldberg, T. L. (2016). Reorganization and expansion of the nidoviral family Arteriviridae. Archives of Virology, 161(3), 755-768. https://doi.org/10.1007/s00705-015-2672-z